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Page 1
GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways.
Guerenne L, Beurlet S, Said M, Gorombei P, Le Pogam C, Guidez F, de la Grange P, Omidvar N, Vanneaux V, Mills K, Mufti GJ, Sarda-Mantel L, Noguera ME, Pla M, Fenaux P, Padua RA, Chomienne C, Krief P. Guerenne L, et al. J Hematol Oncol. 2016 Jan 27;9:5. doi: 10.1186/s13045-016-0235-8. J Hematol Oncol. 2016. PMID: 26817437 Free PMC article.
DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies.
Le Pogam C, Patel S, Gorombei P, Guerenne L, Krief P, Omidvar N, Tekin N, Bernasconi E, Sicre F, Schlageter MH, Chopin M, Noguera ME, West R, Abu A, Mathews V, Pla M, Fenaux P, Chomienne C, Padua RA. Le Pogam C, et al. Among authors: guerenne l. Oncotarget. 2015 Oct 20;6(32):32494-508. doi: 10.18632/oncotarget.5572. Oncotarget. 2015. PMID: 26378812 Free PMC article.
BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
Gorombei P, Guidez F, Ganesan S, Chiquet M, Pellagatti A, Goursaud L, Tekin N, Beurlet S, Patel S, Guerenne L, Le Pogam C, Setterblad N, de la Grange P, LeBoeuf C, Janin A, Noguera ME, Sarda-Mantel L, Merlet P, Boultwood J, Konopleva M, Andreeff M, West R, Pla M, Adès L, Fenaux P, Krief P, Chomienne C, Omidvar N, Padua RA. Gorombei P, et al. Among authors: guerenne l. Int J Mol Sci. 2021 Sep 30;22(19):10658. doi: 10.3390/ijms221910658. Int J Mol Sci. 2021. PMID: 34638998 Free PMC article.
pVAX14DNA-mediated add-on immunotherapy combined with arsenic trioxide and all-trans retinoic acid targeted therapy effectively increases the survival of acute promyelocytic leukemia mice.
Patel S, Guerenne L, Gorombei P, Omidvar N, Schlageter MH, Alex AA, Ganesan S, West R, Adès L, Mathews V, Krief P, Pla M, Fenaux P, Chomienne C, Padua RA. Patel S, et al. Among authors: guerenne l. Blood Cancer J. 2015 Dec 11;5(12):e374. doi: 10.1038/bcj.2015.102. Blood Cancer J. 2015. PMID: 26657197 Free PMC article. No abstract available.