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Page 1
Novel C-Ring-Hydroxy-Substituted Controlled Deactivation Cannabinergic Analogues.
Kulkarni S, Nikas SP, Sharma R, Jiang S, Paronis CA, Leonard MZ, Zhang B, Honrao C, Mallipeddi S, Raghav JG, Benchama O, Järbe TU, Bergman J, Makriyannis A. Kulkarni S, et al. Among authors: leonard mz. J Med Chem. 2016 Jul 28;59(14):6903-19. doi: 10.1021/acs.jmedchem.6b00717. Epub 2016 Jul 13. J Med Chem. 2016. PMID: 27367336 Free PMC article.
The neutral CB1 antagonist AM6527 reduces ethanol seeking, binge-like consumption, reinforcing, and withdrawal effects in male and female mice.
Raghav JG, Kumar H, Ji L, Vemuri K, Makriyannis A, Suh J, Leonard MZ, Dang V, Ty C, Marandola S, Kane N, Witt AS, Shaqour S, Miczek KA. Raghav JG, et al. Among authors: leonard mz. Psychopharmacology (Berl). 2024 Mar;241(3):427-443. doi: 10.1007/s00213-023-06500-w. Epub 2023 Nov 25. Psychopharmacology (Berl). 2024. PMID: 38001264
Systemic inhibition of de novo purine biosynthesis prevents weight gain and improves metabolic health by increasing thermogenesis and decreasing food intake.
Myers JW, Park WY, Eddie AM, Shinde AB, Prasad P, Murphy AC, Leonard MZ, Pinette JA, Rampy JJ, Montufar C, Shaikh Z, Hickman TT, Reynolds GN, Winn NC, Lantier L, Peck SH, Coate KC, Stein RW, Carrasco N, Calipari ES, McReynolds MR, Zaganjor E. Myers JW, et al. Among authors: leonard mz. bioRxiv [Preprint]. 2024 Nov 1:2024.10.28.620705. doi: 10.1101/2024.10.28.620705. bioRxiv. 2024. PMID: 39553975 Free PMC article. Preprint.
A Cocaine-Activated Ensemble Exerts Increased Control Over Behavior While Decreasing in Size.
Thibeault KC, Leonard MZ, Kondev V, Emerson SD, Bethi R, Lopez AJ, Sens JP, Nabit BP, Elam HB, Winder DG, Patel S, Kiraly DD, Grueter BA, Calipari ES. Thibeault KC, et al. Among authors: leonard mz. Biol Psychiatry. 2024 Jun 18:S0006-3223(24)01388-X. doi: 10.1016/j.biopsych.2024.06.008. Online ahead of print. Biol Psychiatry. 2024. PMID: 38901723 Free article.
D1 and D2 medium spiny neurons in the nucleus accumbens core have distinct and valence-independent roles in learning.
Zachry JE, Kutlu MG, Yoon HJ, Leonard MZ, Chevée M, Patel DD, Gaidici A, Kondev V, Thibeault KC, Bethi R, Tat J, Melugin PR, Isiktas AU, Joffe ME, Cai DJ, Conn PJ, Grueter BA, Calipari ES. Zachry JE, et al. Among authors: leonard mz. Neuron. 2024 Mar 6;112(5):835-849.e7. doi: 10.1016/j.neuron.2023.11.023. Epub 2023 Dec 21. Neuron. 2024. PMID: 38134921
23 results