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Page 1
GFI1 as a novel prognostic and therapeutic factor for AML/MDS.
Hönes JM, Botezatu L, Helness A, Vadnais C, Vassen L, Robert F, Hergenhan SM, Thivakaran A, Schütte J, Al-Matary YS, Lams RF, Fraszscak J, Makishima H, Radivoyevitch T, Przychodzen B, da Conceição Castro SV, Görgens A, Giebel B, Klein-Hitpass L, Lennartz K, Heuser M, Thiede C, Ehninger G, Dührsen U, Maciejewski JP, Möröy T, Khandanpour C. Hönes JM, et al. Among authors: lams rf. Leukemia. 2016 Jun;30(6):1237-45. doi: 10.1038/leu.2016.11. Epub 2016 Feb 5. Leukemia. 2016. PMID: 26847026
Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.
Botezatu L, Michel LC, Helness A, Vadnais C, Makishima H, Hönes JM, Robert F, Vassen L, Thivakaran A, Al-Matary Y, Lams RF, Schütte J, Giebel B, Görgens A, Heuser M, Medyouf H, Maciejewski J, Dührsen U, Möröy T, Khandanpour C. Botezatu L, et al. Among authors: lams rf. Exp Hematol. 2016 Aug;44(8):713-726.e14. doi: 10.1016/j.exphem.2016.05.004. Epub 2016 May 20. Exp Hematol. 2016. PMID: 27216773 Free article.
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.
Al-Matary YS, Botezatu L, Opalka B, Hönes JM, Lams RF, Thivakaran A, Schütte J, Köster R, Lennartz K, Schroeder T, Haas R, Dührsen U, Khandanpour C. Al-Matary YS, et al. Among authors: lams rf. Haematologica. 2016 Oct;101(10):1216-1227. doi: 10.3324/haematol.2016.143180. Epub 2016 Jul 7. Haematologica. 2016. PMID: 27390361 Free PMC article.
GFI1 is required for RUNX1/ETO positive acute myeloid leukemia.
Marneth AE, Botezatu L, Hönes JM, Israël JCL, Schütte J, Vassen L, Lams RF, Bergevoet SM, Groothuis L, Mandoli A, Martens JHA, Huls G, Jansen JH, Dührsen U, Berg T, Möröy T, Wichmann C, Lo MC, Zhang DE, van der Reijden BA, Khandanpour C. Marneth AE, et al. Among authors: lams rf. Haematologica. 2018 Sep;103(9):e395-e399. doi: 10.3324/haematol.2017.180844. Epub 2018 Apr 19. Haematologica. 2018. PMID: 29674496 Free PMC article. No abstract available.