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Prions activate a p38 MAPK synaptotoxic signaling pathway.
Fang C, Wu B, Le NTT, Imberdis T, Mercer RCC, Harris DA. Fang C, et al. Among authors: imberdis t. PLoS Pathog. 2018 Sep 20;14(9):e1007283. doi: 10.1371/journal.ppat.1007283. eCollection 2018 Sep. PLoS Pathog. 2018. PMID: 30235355 Free PMC article.
A Neuronal Culture System to Detect Prion Synaptotoxicity.
Fang C, Imberdis T, Garza MC, Wille H, Harris DA. Fang C, et al. Among authors: imberdis t. PLoS Pathog. 2016 May 26;12(5):e1005623. doi: 10.1371/journal.ppat.1005623. eCollection 2016 May. PLoS Pathog. 2016. PMID: 27227882 Free PMC article.
Identification of Anti-prion Compounds using a Novel Cellular Assay.
Imberdis T, Heeres JT, Yueh H, Fang C, Zhen J, Rich CB, Glicksman M, Beeler AB, Harris DA. Imberdis T, et al. J Biol Chem. 2016 Dec 9;291(50):26164-26176. doi: 10.1074/jbc.M116.745612. Epub 2016 Nov 1. J Biol Chem. 2016. PMID: 27803163 Free PMC article.
Low doses of bioherbicide favour prion aggregation and propagation in vivo.
Lafon PA, Imberdis T, Wang Y, Torrent J, Robitzer M, Huetter E, Alvarez-Martinez MT, Chevallier N, Givalois L, Desrumaux C, Liu J, Perrier V. Lafon PA, et al. Among authors: imberdis t. Sci Rep. 2018 May 23;8(1):8023. doi: 10.1038/s41598-018-25966-9. Sci Rep. 2018. PMID: 29795181 Free PMC article.
Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase.
Imberdis T, Negri J, Ramalingam N, Terry-Kantor E, Ho GPH, Fanning S, Stirtz G, Kim TE, Levy OA, Young-Pearse TL, Selkoe D, Dettmer U. Imberdis T, et al. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20760-20769. doi: 10.1073/pnas.1903216116. Epub 2019 Sep 23. Proc Natl Acad Sci U S A. 2019. PMID: 31548371 Free PMC article.
22 results