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WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
Yang CL, Angell J, Mitchell R, Ellison DH. Yang CL, et al. Among authors: ellison dh. J Clin Invest. 2003 Apr;111(7):1039-45. doi: 10.1172/JCI17443. J Clin Invest. 2003. PMID: 12671053 Free PMC article.
WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Chávez-Canales M, Zhang C, Soukaseum C, Moreno E, Pacheco-Alvarez D, Vidal-Petiot E, Castañeda-Bueno M, Vázquez N, Rojas-Vega L, Meermeier NP, Rogers S, Jeunemaitre X, Yang CL, Ellison DH, Gamba G, Hadchouel J. Chávez-Canales M, et al. Among authors: ellison dh. Hypertension. 2014 Nov;64(5):1047-53. doi: 10.1161/HYPERTENSIONAHA.114.04036. Epub 2014 Aug 11. Hypertension. 2014. PMID: 25113964 Free PMC article.
Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.
McCormick JA, Yang CL, Zhang C, Davidge B, Blankenstein KI, Terker AS, Yarbrough B, Meermeier NP, Park HJ, McCully B, West M, Borschewski A, Himmerkus N, Bleich M, Bachmann S, Mutig K, Argaiz ER, Gamba G, Singer JD, Ellison DH. McCormick JA, et al. Among authors: ellison dh. J Clin Invest. 2014 Nov;124(11):4723-36. doi: 10.1172/JCI76126. Epub 2014 Sep 24. J Clin Invest. 2014. PMID: 25250572 Free PMC article.
The Effect of WNK4 on the Na+-Cl- Cotransporter Is Modulated by Intracellular Chloride.
Bazúa-Valenti S, Chávez-Canales M, Rojas-Vega L, González-Rodríguez X, Vázquez N, Rodríguez-Gama A, Argaiz ER, Melo Z, Plata C, Ellison DH, García-Valdés J, Hadchouel J, Gamba G. Bazúa-Valenti S, et al. Among authors: ellison dh. J Am Soc Nephrol. 2015 Aug;26(8):1781-6. doi: 10.1681/ASN.2014050470. Epub 2014 Dec 26. J Am Soc Nephrol. 2015. PMID: 25542968 Free PMC article.
200 results