Moore DD - Search Results

1

Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis.

Gomez-Ospina N, Potter CJ, Xiao R, Manickam K, Kim MS, Kim KH, Shneider BL, Picarsic JL, Jacobson TA, Zhang J, He W, Liu P, Knisely AS, Finegold MJ, Muzny DM, Boerwinkle E, Lupski JR, Plon SE, Gibbs RA, Eng CM, Yang Y, Washington GC, Porteus MH, Berquist WE, Kambham N, Singh RJ, Xia F, Enns GM, Moore DD. Gomez-Ospina N, et al. Among authors: moore dd. Nat Commun. 2016 Feb 18;7:10713. doi: 10.1038/ncomms10713. Nat Commun. 2016. PMID: 26888176 Free PMC article.

2

The farnesoid X-activated receptor mediates bile acid activation of phospholipid transfer protein gene expression.

Urizar NL, Dowhan DH, Moore DD. Urizar NL, et al. Among authors: moore dd. J Biol Chem. 2000 Dec 15;275(50):39313-7. doi: 10.1074/jbc.M007998200. J Biol Chem. 2000. PMID: 10998425 Free article.

3

The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism.

Wei P, Zhang J, Egan-Hafley M, Liang S, Moore DD. Wei P, et al. Among authors: moore dd. Nature. 2000 Oct 19;407(6806):920-3. doi: 10.1038/35038112. Nature. 2000. PMID: 11057673

4

Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.

Wei P, Zhang J, Dowhan DH, Han Y, Moore DD. Wei P, et al. Among authors: moore dd. Pharmacogenomics J. 2002;2(2):117-26. doi: 10.1038/sj.tpj.6500087. Pharmacogenomics J. 2002. PMID: 12049174

5

Redundant pathways for negative feedback regulation of bile acid production.

Wang L, Lee YK, Bundman D, Han Y, Thevananther S, Kim CS, Chua SS, Wei P, Heyman RA, Karin M, Moore DD. Wang L, et al. Among authors: moore dd. Dev Cell. 2002 Jun;2(6):721-31. doi: 10.1016/s1534-5807(02)00187-9. Dev Cell. 2002. PMID: 12062085 Free article.

6

Resistance of SHP-null mice to bile acid-induced liver damage.

Wang L, Han Y, Kim CS, Lee YK, Moore DD. Wang L, et al. Among authors: moore dd. J Biol Chem. 2003 Nov 7;278(45):44475-81. doi: 10.1074/jbc.M305258200. Epub 2003 Aug 21. J Biol Chem. 2003. PMID: 12933814 Free article.

7

Nuclear receptor-dependent bile acid signaling is required for normal liver regeneration.

Huang W, Ma K, Zhang J, Qatanani M, Cuvillier J, Liu J, Dong B, Huang X, Moore DD. Huang W, et al. Among authors: moore dd. Science. 2006 Apr 14;312(5771):233-6. doi: 10.1126/science.1121435. Science. 2006. PMID: 16614213

8

International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D receptor.

Moore DD, Kato S, Xie W, Mangelsdorf DJ, Schmidt DR, Xiao R, Kliewer SA. Moore DD, et al. Pharmacol Rev. 2006 Dec;58(4):742-59. doi: 10.1124/pr.58.4.6. Pharmacol Rev. 2006. PMID: 17132852 Review.

9

Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR.

Carter BA, Taylor OA, Prendergast DR, Zimmerman TL, Von Furstenberg R, Moore DD, Karpen SJ. Carter BA, et al. Among authors: moore dd. Pediatr Res. 2007 Sep;62(3):301-6. doi: 10.1203/PDR.0b013e3181256492. Pediatr Res. 2007. PMID: 17622954

10

Loss of orphan receptor small heterodimer partner sensitizes mice to liver injury from obstructive cholestasis.

Park YJ, Qatanani M, Chua SS, LaRey JL, Johnson SA, Watanabe M, Moore DD, Lee YK. Park YJ, et al. Among authors: moore dd. Hepatology. 2008 May;47(5):1578-86. doi: 10.1002/hep.22196. Hepatology. 2008. PMID: 18393320

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