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Using single nuclei for RNA-seq to capture the transcriptome of postmortem neurons.
Krishnaswami SR, Grindberg RV, Novotny M, Venepally P, Lacar B, Bhutani K, Linker SB, Pham S, Erwin JA, Miller JA, Hodge R, McCarthy JK, Kelder M, McCorrison J, Aevermann BD, Fuertes FD, Scheuermann RH, Lee J, Lein ES, Schork N, McConnell MJ, Gage FH, Lasken RS. Krishnaswami SR, et al. Among authors: mcconnell mj. Nat Protoc. 2016 Mar;11(3):499-524. doi: 10.1038/nprot.2016.015. Epub 2016 Feb 18. Nat Protoc. 2016. PMID: 26890679 Free PMC article.
Mice lacking methyl-CpG binding protein 1 have deficits in adult neurogenesis and hippocampal function.
Zhao X, Ueba T, Christie BR, Barkho B, McConnell MJ, Nakashima K, Lein ES, Eadie BD, Willhoite AR, Muotri AR, Summers RG, Chun J, Lee KF, Gage FH. Zhao X, et al. Among authors: mcconnell mj. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6777-82. doi: 10.1073/pnas.1131928100. Epub 2003 May 14. Proc Natl Acad Sci U S A. 2003. PMID: 12748381 Free PMC article.
Mosaic copy number variation in human neurons.
McConnell MJ, Lindberg MR, Brennand KJ, Piper JC, Voet T, Cowing-Zitron C, Shumilina S, Lasken RS, Vermeesch JR, Hall IM, Gage FH. McConnell MJ, et al. Science. 2013 Nov 1;342(6158):632-7. doi: 10.1126/science.1243472. Science. 2013. PMID: 24179226 Free PMC article.
RNA-sequencing from single nuclei.
Grindberg RV, Yee-Greenbaum JL, McConnell MJ, Novotny M, O'Shaughnessy AL, Lambert GM, Araúzo-Bravo MJ, Lee J, Fishman M, Robbins GE, Lin X, Venepally P, Badger JH, Galbraith DW, Gage FH, Lasken RS. Grindberg RV, et al. Among authors: mcconnell mj. Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):19802-7. doi: 10.1073/pnas.1319700110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248345 Free PMC article.
Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJE, Parylak SL, Paquola ACM, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. Lacar B, et al. Among authors: mcconnell mj. Nat Commun. 2016 Apr 19;7:11022. doi: 10.1038/ncomms11022. Nat Commun. 2016. PMID: 27090946 Free PMC article.
Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. Lacar B, et al. Among authors: mcconnell mj. Nat Commun. 2016 Jun 14;7:12020. doi: 10.1038/ncomms12020. Nat Commun. 2016. PMID: 27295945 Free PMC article. No abstract available.
Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation.
Lacar B, Linker SB, Jaeger BN, Krishnaswami SR, Barron JJ, Kelder MJ, Parylak SL, Paquola AC, Venepally P, Novotny M, O'Connor C, Fitzpatrick C, Erwin JA, Hsu JY, Husband D, McConnell MJ, Lasken R, Gage FH. Lacar B, et al. Among authors: mcconnell mj. Nat Commun. 2017 Mar 17;8:15047. doi: 10.1038/ncomms15047. Nat Commun. 2017. PMID: 28303884 Free PMC article. No abstract available.
192 results