Structural Basis for Iron-Mediated Sulfur Transfer in Archael and Yeast Thiazole Synthases.
Zhang X, Eser BE, Chanani PK, Begley TP, Ealick SE.
Zhang X, et al.
Biochemistry. 2016 Mar 29;55(12):1826-38. doi: 10.1021/acs.biochem.6b00030. Epub 2016 Mar 10.
Biochemistry. 2016.
PMID: 26919468
Free PMC article.
Our recent biochemical studies showed that the archael Thi4 orthologs use nicotinamide adenine dinucleotide, glycine, and free sulfide to form the thiamin thiazole in an iron-dependent reaction [Eser, B., Zhang, X., Chanani, P. K., Begley, T. P., and Ealick, S. E. ( …
Our recent biochemical studies showed that the archael Thi4 orthologs use nicotinamide adenine dinucleotide, glycine, and free sulfide to fo …