Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice.
Yura Y, Chong BSH, Johnson RD, Watanabe Y, Tsukahara Y, Ferran B, Murdoch CE, Behring JB, McComb ME, Costello CE, Janssen-Heininger YMW, Cohen RA, Bachschmid MM, Matsui R.
Yura Y, et al. Among authors: watanabe y.
FASEB J. 2019 Dec;33(12):14147-14158. doi: 10.1096/fj.201900786R. Epub 2019 Oct 26.
FASEB J. 2019.
PMID: 31647879
Free PMC article.
These data suggest that impaired ischemic vascularization does not necessarily associate with suppression of tumor growth, and that antiangiogenic therapies may be ineffective for melanoma tumors because of their ability to implement vasculogenic mimicry during hypoxia.-Yura, …
These data suggest that impaired ischemic vascularization does not necessarily associate with suppression of tumor growth, and that antiangi …