Kharabi Masouleh B - Search Results

1

Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.

Sun H, Lin DC, Guo X, Kharabi Masouleh B, Gery S, Cao Q, Alkan S, Ikezoe T, Akiba C, Paquette R, Chien W, Müller-Tidow C, Jing Y, Agelopoulos K, Müschen M, Koeffler HP. Sun H, et al. Among authors: kharabi masouleh b. Oncotarget. 2016 Apr 5;7(14):18736-49. doi: 10.18632/oncotarget.7702. Oncotarget. 2016. PMID: 26934650 Free PMC article.

2

Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia.

Kharabi Masouleh B, Geng H, Hurtz C, Chan LN, Logan AC, Chang MS, Huang C, Swaminathan S, Sun H, Paietta E, Melnick AM, Koeffler P, Müschen M. Kharabi Masouleh B, et al. Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2219-28. doi: 10.1073/pnas.1400958111. Epub 2014 May 12. Proc Natl Acad Sci U S A. 2014. PMID: 24821775 Free PMC article.

3

Identification of the Adapter Molecule MTSS1 as a Potential Oncogene-Specific Tumor Suppressor in Acute Myeloid Leukemia.

Schemionek M, Kharabi Masouleh B, Klaile Y, Krug U, Hebestreit K, Schubert C, Dugas M, Büchner T, Wörmann B, Hiddemann W, Berdel WE, Brümmendorf TH, Müller-Tidow C, Koschmieder S. Schemionek M, et al. Among authors: kharabi masouleh b. PLoS One. 2015 May 21;10(5):e0125783. doi: 10.1371/journal.pone.0125783. eCollection 2015. PLoS One. 2015. PMID: 25996952 Free PMC article.

4

Infliction of proteotoxic stresses by impairment of the unfolded protein response or proteasomal inhibition as a therapeutic strategy for mast cell leukemia.

Wilhelm T, Bick F, Peters K, Mohta V, Tirosh B, Patterson JB, Kharabi-Masouleh B, Huber M. Wilhelm T, et al. Among authors: kharabi masouleh b. Oncotarget. 2017 Dec 17;9(3):2984-3000. doi: 10.18632/oncotarget.23354. eCollection 2018 Jan 9. Oncotarget. 2017. PMID: 29423023 Free PMC article.

5

Targeting of BCR-ABL1 and IRE1α induces synthetic lethality in Philadelphia-positive acute lymphoblastic leukemia.

Vieri M, Preisinger C, Schemionek M, Salimi A, Patterson JB, Samali A, Brümmendorf TH, Appelmann I, Kharabi Masouleh B. Vieri M, et al. Among authors: kharabi masouleh b. Carcinogenesis. 2021 Feb 25;42(2):272-284. doi: 10.1093/carcin/bgaa095. Carcinogenesis. 2021. PMID: 32915195

6

Drugging the unfolded protein response in acute leukemias.

Kharabi Masouleh B, Chevet E, Panse J, Jost E, O'Dwyer M, Bruemmendorf TH, Samali A. Kharabi Masouleh B, et al. J Hematol Oncol. 2015 Jul 16;8:87. doi: 10.1186/s13045-015-0184-7. J Hematol Oncol. 2015. PMID: 26179601 Free PMC article. Review.

7

Targeting the angio-proteostasis network: Combining the forces against cancer.

Devisscher L, Vieri M, Logue SE, Panse J, Geerts A, van Vlierberghe H, Chevet E, Gorman AM, Samali A, Kharabi Masouleh B. Devisscher L, et al. Among authors: kharabi masouleh b. Pharmacol Ther. 2016 Nov;167:1-12. doi: 10.1016/j.pharmthera.2016.07.007. Epub 2016 Jul 22. Pharmacol Ther. 2016. PMID: 27452337

8

A three-gene expression-based risk score can refine the European LeukemiaNet AML classification.

Wilop S, Chou WC, Jost E, Crysandt M, Panse J, Chuang MK, Brümmendorf TH, Wagner W, Tien HF, Kharabi Masouleh B. Wilop S, et al. Among authors: kharabi masouleh b. J Hematol Oncol. 2016 Sep 1;9(1):78. doi: 10.1186/s13045-016-0308-8. J Hematol Oncol. 2016. PMID: 27585840 Free PMC article.

9

Deregulated expression of the HSP40 family members Auxilin-1 and -2 is indicative of proteostasis imbalance and predicts patient outcome in Ph(+) leukemia.

Vieri M, Geng H, Patterson JB, Panse J, Wilop S, Samali A, Chevet E, Kharabi Masouleh B. Vieri M, et al. Among authors: kharabi masouleh b. Exp Hematol Oncol. 2016 Feb 9;5:5. doi: 10.1186/s40164-016-0034-5. eCollection 2015. Exp Hematol Oncol. 2016. PMID: 26862466 Free PMC article.

10

XBP1 promotes NRAS^G12D pre-B acute lymphoblastic leukaemia through IL-7 receptor signalling and provides a therapeutic vulnerability for oncogenic RAS.

Salimi A, Schemionek-Reinders M, Huber M, Vieri M, Patterson JB, Alten J, Brümmendorf TH, Kharabi Masouleh B, Appelmann I. Salimi A, et al. Among authors: kharabi masouleh b. J Cell Mol Med. 2023 Nov;27(21):3363-3377. doi: 10.1111/jcmm.17904. Epub 2023 Sep 27. J Cell Mol Med. 2023. PMID: 37753803 Free PMC article.

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