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Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction.
Pawlinski R, Fernandes A, Kehrle B, Pedersen B, Parry G, Erlich J, Pyo R, Gutstein D, Zhang J, Castellino F, Melis E, Carmeliet P, Baretton G, Luther T, Taubman M, Rosen E, Mackman N. Pawlinski R, et al. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15333-8. doi: 10.1073/pnas.242501899. Epub 2002 Nov 8. Proc Natl Acad Sci U S A. 2002. PMID: 12426405 Free PMC article.
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice.
Schabbauer G, Tencati M, Pedersen B, Pawlinski R, Mackman N. Schabbauer G, et al. Among authors: pawlinski r. Arterioscler Thromb Vasc Biol. 2004 Oct;24(10):1963-9. doi: 10.1161/01.ATV.0000143096.15099.ce. Epub 2004 Aug 19. Arterioscler Thromb Vasc Biol. 2004. PMID: 15319270
Atherosclerosis in mice is not affected by a reduction in tissue factor expression.
Tilley RE, Pedersen B, Pawlinski R, Sato Y, Erlich JH, Shen Y, Day S, Huang Y, Eitzman DT, Boisvert WA, Curtiss LK, Fay WP, Mackman N. Tilley RE, et al. Among authors: pawlinski r. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):555-62. doi: 10.1161/01.ATV.0000202028.62414.3c. Epub 2005 Dec 29. Arterioscler Thromb Vasc Biol. 2006. PMID: 16385085
99 results