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Page 1
IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L. Iannitti RG, et al. Nat Commun. 2016 Mar 14;7:10791. doi: 10.1038/ncomms10791. Nat Commun. 2016. PMID: 26972847 Free PMC article.
Hypoxia promotes danger-mediated inflammation via receptor for advanced glycation end products in cystic fibrosis.
Iannitti RG, Casagrande A, De Luca A, Cunha C, Sorci G, Riuzzi F, Borghi M, Galosi C, Massi-Benedetti C, Oury TD, Cariani L, Russo M, Porcaro L, Colombo C, Majo F, Lucidi V, Fiscarelli E, Ricciotti G, Lass-Flörl C, Ratclif L, Esposito A, De Benedictis FM, Donato R, Carvalho A, Romani L. Iannitti RG, et al. Am J Respir Crit Care Med. 2013 Dec 1;188(11):1338-50. doi: 10.1164/rccm.201305-0986OC. Am J Respir Crit Care Med. 2013. PMID: 24127697
IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis.
Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. Moretti S, et al. Among authors: iannitti rg. PLoS Pathog. 2014 Nov 6;10(11):e1004462. doi: 10.1371/journal.ppat.1004462. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25375146 Free PMC article.
A mast cell-ILC2-Th9 pathway promotes lung inflammation in cystic fibrosis.
Moretti S, Renga G, Oikonomou V, Galosi C, Pariano M, Iannitti RG, Borghi M, Puccetti M, De Zuani M, Pucillo CE, Paolicelli G, Zelante T, Renauld JC, Bereshchenko O, Sportoletti P, Lucidi V, Russo MC, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Ricciotti G, Ellemunter H, Ratclif L, Talesa VN, Napolioni V, Romani L. Moretti S, et al. Among authors: iannitti rg. Nat Commun. 2017 Jan 16;8:14017. doi: 10.1038/ncomms14017. Nat Commun. 2017. PMID: 28090087 Free PMC article.
Sensing of mammalian IL-17A regulates fungal adaptation and virulence.
Zelante T, Iannitti RG, De Luca A, Arroyo J, Blanco N, Servillo G, Sanglard D, Reichard U, Palmer GE, Latgè JP, Puccetti P, Romani L. Zelante T, et al. Among authors: iannitti rg. Nat Commun. 2012 Feb 21;3:683. doi: 10.1038/ncomms1685. Nat Commun. 2012. PMID: 22353714 Free article.
Th17/Treg imbalance in murine cystic fibrosis is linked to indoleamine 2,3-dioxygenase deficiency but corrected by kynurenines.
Iannitti RG, Carvalho A, Cunha C, De Luca A, Giovannini G, Casagrande A, Zelante T, Vacca C, Fallarino F, Puccetti P, Massi-Benedetti C, Defilippi G, Russo M, Porcaro L, Colombo C, Ratclif L, De Benedictis FM, Romani L. Iannitti RG, et al. Am J Respir Crit Care Med. 2013 Mar 15;187(6):609-20. doi: 10.1164/rccm.201207-1346OC. Epub 2013 Jan 10. Am J Respir Crit Care Med. 2013. PMID: 23306541
Thymosin α1 represents a potential potent single-molecule-based therapy for cystic fibrosis.
Romani L, Oikonomou V, Moretti S, Iannitti RG, D'Adamo MC, Villella VR, Pariano M, Sforna L, Borghi M, Bellet MM, Fallarino F, Pallotta MT, Servillo G, Ferrari E, Puccetti P, Kroemer G, Pessia M, Maiuri L, Goldstein AL, Garaci E. Romani L, et al. Among authors: iannitti rg. Nat Med. 2017 May;23(5):590-600. doi: 10.1038/nm.4305. Epub 2017 Apr 10. Nat Med. 2017. PMID: 28394330 Free PMC article.
Anakinra Activates Superoxide Dismutase 2 to Mitigate Inflammasome Activity.
Pariano M, Pieroni S, De Luca A, Iannitti RG, Borghi M, Puccetti M, Giovagnoli S, Renga G, D'Onofrio F, Bellet MM, Stincardini C, Della-Fazia MA, Servillo G, van de Veerdonk FL, Costantini C, Romani L. Pariano M, et al. Among authors: iannitti rg. Int J Mol Sci. 2021 Jun 18;22(12):6531. doi: 10.3390/ijms22126531. Int J Mol Sci. 2021. PMID: 34207085 Free PMC article.
Anakinra restores cellular proteostasis by coupling mitochondrial redox balance to autophagy.
van de Veerdonk FL, Renga G, Pariano M, Bellet MM, Servillo G, Fallarino F, De Luca A, Iannitti RG, Piobbico D, Gargaro M, Manni G, D'Onofrio F, Stincardini C, Sforna L, Borghi M, Castelli M, Pieroni S, Oikonomou V, Villella VR, Puccetti M, Giovagnoli S, Galarini R, Barola C, Maiuri L, Della Fazia MA, Cellini B, Talesa VN, Dinarello CA, Costantini C, Romani L. van de Veerdonk FL, et al. Among authors: iannitti rg. J Clin Invest. 2022 Jan 18;132(2):e144983. doi: 10.1172/JCI144983. J Clin Invest. 2022. PMID: 34847078 Free PMC article.
IL-22 in antifungal immunity.
Zelante T, Iannitti R, De Luca A, Romani L. Zelante T, et al. Eur J Immunol. 2011 Feb;41(2):270-5. doi: 10.1002/eji.201041246. Epub 2011 Jan 11. Eur J Immunol. 2011. PMID: 21267995 Free article. Review.
42 results