Üren A - Search Results

1

Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer.

Roudier MP, Winters BR, Coleman I, Lam HM, Zhang X, Coleman R, Chéry L, True LD, Higano CS, Montgomery B, Lange PH, Snyder LA, Srivastava S, Corey E, Vessella RL, Nelson PS, Üren A, Morrissey C. Roudier MP, et al. Among authors: uren a. Prostate. 2016 Jun;76(9):810-22. doi: 10.1002/pros.23171. Epub 2016 Mar 16. Prostate. 2016. PMID: 26990456 Free PMC article.

2

YK-4-279 inhibits ERG and ETV1 mediated prostate cancer cell invasion.

Rahim S, Beauchamp EM, Kong Y, Brown ML, Toretsky JA, Üren A. Rahim S, et al. Among authors: uren a. PLoS One. 2011 Apr 29;6(4):e19343. doi: 10.1371/journal.pone.0019343. PLoS One. 2011. PMID: 21559405 Free PMC article.

3

Inhibition of ERG Activity in Patient-derived Prostate Cancer Xenografts by YK-4-279.

Winters B, Brown L, Coleman I, Nguyen H, Minas TZ, Kollath L, Vasioukhin V, Nelson P, Corey E, Üren A, Morrissey C. Winters B, et al. Among authors: uren a. Anticancer Res. 2017 Jul;37(7):3385-3396. doi: 10.21873/anticanres.11705. Anticancer Res. 2017. PMID: 28668826

4

A small molecule inhibitor of ETV1, YK-4-279, prevents prostate cancer growth and metastasis in a mouse xenograft model.

Rahim S, Minas T, Hong SH, Justvig S, Çelik H, Kont YS, Han J, Kallarakal AT, Kong Y, Rudek MA, Brown ML, Kallakury B, Toretsky JA, Üren A. Rahim S, et al. Among authors: uren a. PLoS One. 2014 Dec 5;9(12):e114260. doi: 10.1371/journal.pone.0114260. eCollection 2014. PLoS One. 2014. PMID: 25479232 Free PMC article.

5

GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.

Beauchamp E, Bulut G, Abaan O, Chen K, Merchant A, Matsui W, Endo Y, Rubin JS, Toretsky J, Uren A. Beauchamp E, et al. Among authors: uren a. J Biol Chem. 2009 Apr 3;284(14):9074-82. doi: 10.1074/jbc.M806233200. Epub 2009 Feb 3. J Biol Chem. 2009. PMID: 19189974 Free PMC article.

6

Arsenic trioxide inhibits human cancer cell growth and tumor development in mice by blocking Hedgehog/GLI pathway.

Beauchamp EM, Ringer L, Bulut G, Sajwan KP, Hall MD, Lee YC, Peaceman D, Ozdemirli M, Rodriguez O, Macdonald TJ, Albanese C, Toretsky JA, Uren A. Beauchamp EM, et al. Among authors: uren a. J Clin Invest. 2011 Jan;121(1):148-60. doi: 10.1172/JCI42874. Epub 2010 Dec 22. J Clin Invest. 2011. PMID: 21183792 Free PMC article.

7

Regulation of the unfolded protein response through ATF4 and FAM129A in prostate cancer.

Pällmann N, Livgård M, Tesikova M, Zeynep Nenseth H, Akkus E, Sikkeland J, Jin Y, Koc D, Kuzu OF, Pradhan M, Danielsen HE, Kahraman N, Mokhlis HM, Ozpolat B, Banerjee PP, Uren A, Fazli L, Rennie PS, Jin Y, Saatcioglu F. Pällmann N, et al. Among authors: uren a. Oncogene. 2019 Aug;38(35):6301-6318. doi: 10.1038/s41388-019-0879-2. Epub 2019 Jul 16. Oncogene. 2019. PMID: 31312022

8

Development of an Ewing sarcoma cell line with resistance to EWS‑FLI1 inhibitor YK‑4‑279.

Conn E, Hour S, Allegakoen D, Graham G, Petro J, Kouassi-Brou M, Hong SH, Selvanathan S, Çelik H, Toretsky J, Üren A. Conn E, et al. Among authors: uren a. Mol Med Rep. 2020 Mar;21(3):1667-1675. doi: 10.3892/mmr.2020.10948. Epub 2020 Jan 16. Mol Med Rep. 2020. PMID: 32016454 Free PMC article.

9

PTPL1 is a direct transcriptional target of EWS-FLI1 and modulates Ewing's Sarcoma tumorigenesis.

Abaan OD, Levenson A, Khan O, Furth PA, Uren A, Toretsky JA. Abaan OD, et al. Among authors: uren a. Oncogene. 2005 Apr 14;24(16):2715-22. doi: 10.1038/sj.onc.1208247. Oncogene. 2005. PMID: 15782144

10

Wnt10b induces chemotaxis of osteosarcoma and correlates with reduced survival.

Chen K, Fallen S, Abaan HO, Hayran M, Gonzalez C, Wodajo F, MacDonald T, Toretsky JA, Uren A. Chen K, et al. Among authors: uren a. Pediatr Blood Cancer. 2008 Sep;51(3):349-55. doi: 10.1002/pbc.21595. Pediatr Blood Cancer. 2008. PMID: 18465804

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