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Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells.
Gambade A, Zreika S, Guéguinou M, Chourpa I, Fromont G, Bouchet AM, Burlaud-Gaillard J, Potier-Cartereau M, Roger S, Aucagne V, Chevalier S, Vandier C, Goupille C, Weber G. Gambade A, et al. Among authors: weber g. Oncotarget. 2016 Apr 26;7(17):23785-800. doi: 10.18632/oncotarget.8122. Oncotarget. 2016. PMID: 26993604 Free PMC article.
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: weber g. Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786. Oncotarget. 2016. PMID: 27102434 Free PMC article.
Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research.
Potier-Cartereau M, Raoul W, Weber G, Mahéo K, Rapetti-Mauss R, Gueguinou M, Buscaglia P, Goupille C, Le Goux N, Abdoul-Azize S, Lecomte T, Fromont G, Chantome A, Mignen O, Soriani O, Vandier C. Potier-Cartereau M, et al. Among authors: weber g. Rev Physiol Biochem Pharmacol. 2022;183:157-176. doi: 10.1007/112_2020_24. Rev Physiol Biochem Pharmacol. 2022. PMID: 32767122
Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume.
Guéguinou M, Felix R, Marionneau-Lambot S, Oullier T, Penna A, Kouba S, Gambade A, Fourbon Y, Ternant D, Arnoult C, Simon G, Bouchet AM, Chantôme A, Harnois T, Haelters JP, Jaffrès PA, Weber G, Bougnoux P, Carreaux F, Mignen O, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Among authors: weber g. Cell Calcium. 2021 Jun 12;97:102435. doi: 10.1016/j.ceca.2021.102435. Online ahead of print. Cell Calcium. 2021. PMID: 34167050
2,622 results