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Oct4 plays a crucial role in the maintenance of gefitinib-resistant lung cancer stem cells.
Kobayashi I, Takahashi F, Nurwidya F, Nara T, Hashimoto M, Murakami A, Yagishita S, Tajima K, Hidayat M, Shimada N, Suina K, Yoshioka Y, Sasaki S, Moriyama M, Moriyama H, Takahashi K. Kobayashi I, et al. Among authors: nara t. Biochem Biophys Res Commun. 2016 Apr 22;473(1):125-132. doi: 10.1016/j.bbrc.2016.03.064. Epub 2016 Mar 17. Biochem Biophys Res Commun. 2016. PMID: 26996130
Hypoxia induces gefitinib resistance in non-small-cell lung cancer with both mutant and wild-type epidermal growth factor receptors.
Minakata K, Takahashi F, Nara T, Hashimoto M, Tajima K, Murakami A, Nurwidya F, Yae S, Koizumi F, Moriyama H, Seyama K, Nishio K, Takahashi K. Minakata K, et al. Among authors: nara t. Cancer Sci. 2012 Nov;103(11):1946-54. doi: 10.1111/j.1349-7006.2012.02408.x. Epub 2012 Sep 14. Cancer Sci. 2012. PMID: 22863020 Free PMC article.
Hypoxia increases gefitinib-resistant lung cancer stem cells through the activation of insulin-like growth factor 1 receptor.
Murakami A, Takahashi F, Nurwidya F, Kobayashi I, Minakata K, Hashimoto M, Nara T, Kato M, Tajima K, Shimada N, Iwakami S, Moriyama M, Moriyama H, Koizumi F, Takahashi K. Murakami A, et al. Among authors: nara t. PLoS One. 2014 Jan 28;9(1):e86459. doi: 10.1371/journal.pone.0086459. eCollection 2014. PLoS One. 2014. PMID: 24489728 Free PMC article.
Treatment with insulin-like growth factor 1 receptor inhibitor reverses hypoxia-induced epithelial-mesenchymal transition in non-small cell lung cancer.
Nurwidya F, Takahashi F, Kobayashi I, Murakami A, Kato M, Minakata K, Nara T, Hashimoto M, Yagishita S, Baskoro H, Hidayat M, Shimada N, Takahashi K. Nurwidya F, et al. Among authors: nara t. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):332-8. doi: 10.1016/j.bbrc.2014.11.014. Epub 2014 Nov 15. Biochem Biophys Res Commun. 2014. PMID: 25446090
Zinc-finger E-box-binding homeobox 1 (ZEB1) plays a crucial role in the maintenance of lung cancer stem cells resistant to gefitinib.
Nurwidya F, Takahashi F, Winardi W, Tajima K, Mitsuishi Y, Murakami A, Kobayashi I, Nara T, Hashimoto M, Kato M, Hidayat M, Suina K, Hayakawa D, Asao T, Ko R, Shukuya T, Yae T, Shimada N, Yoshioka Y, Sasaki S, Takahashi K. Nurwidya F, et al. Among authors: nara t. Thorac Cancer. 2021 May;12(10):1536-1548. doi: 10.1111/1759-7714.13937. Epub 2021 Mar 25. Thorac Cancer. 2021. PMID: 33764690 Free PMC article.
Sex hormones alter Th1 responses and enhance granuloma formation in the lung.
Tajima K, Miura K, Ishiwata T, Takahashi F, Yoshioka M, Minakata K, Murakami A, Sasaki S, Iwakami S, Annoura T, Hashimoto M, Nara T, Takahashi K. Tajima K, et al. Among authors: nara t. Respiration. 2011;81(6):491-8. doi: 10.1159/000324295. Epub 2011 Apr 1. Respiration. 2011. PMID: 21454951
Haploinsufficiency of the folliculin gene leads to impaired functions of lung fibroblasts in patients with Birt-Hogg-Dubé syndrome.
Hoshika Y, Takahashi F, Togo S, Hashimoto M, Nara T, Kobayashi T, Nurwidya F, Kataoka H, Kurihara M, Kobayashi E, Ebana H, Kikkawa M, Ando K, Nishino K, Hino O, Takahashi K, Seyama K. Hoshika Y, et al. Among authors: nara t. Physiol Rep. 2016 Nov;4(21):e13025. doi: 10.14814/phy2.13025. Epub 2016 Nov 15. Physiol Rep. 2016. PMID: 27905298 Free PMC article.
Critical importance of the de novo pyrimidine biosynthesis pathway for Trypanosoma cruzi growth in the mammalian host cell cytoplasm.
Hashimoto M, Morales J, Fukai Y, Suzuki S, Takamiya S, Tsubouchi A, Inoue S, Inoue M, Kita K, Harada S, Tanaka A, Aoki T, Nara T. Hashimoto M, et al. Among authors: nara t. Biochem Biophys Res Commun. 2012 Jan 20;417(3):1002-6. doi: 10.1016/j.bbrc.2011.12.073. Epub 2011 Dec 22. Biochem Biophys Res Commun. 2012. PMID: 22209850
372 results