Walmsley SR - Search Results

1

Mutations in succinate dehydrogenase B (SDHB) enhance neutrophil survival independent of HIF-1α expression.

Jones R, McDonald KE, Willson JA, Ghesquière B, Sammut D, Daniel E, Harris AJ, Lewis A, Thompson AA, Dickinson RS, Plant T, Murphy F, Sadiku P, Keevil BG, Carmeliet P, Whyte MK, Newell-Price J, Walmsley SR. Jones R, et al. Among authors: walmsley sr. Blood. 2016 May 26;127(21):2641-4. doi: 10.1182/blood-2016-02-696922. Epub 2016 Mar 22. Blood. 2016. PMID: 27006389 Free PMC article. No abstract available.

2

Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis.

Walmsley SR, Cowburn AS, Clatworthy MR, Morrell NW, Roper EC, Singleton V, Maxwell P, Whyte MK, Chilvers ER. Walmsley SR, et al. Blood. 2006 Nov 1;108(9):3176-8. doi: 10.1182/blood-2006-04-018796. Epub 2006 Jun 29. Blood. 2006. PMID: 16809612 Free article.

3

The HIF/VHL pathway: from oxygen sensing to innate immunity.

Walmsley SR, McGovern NN, Whyte MK, Chilvers ER. Walmsley SR, et al. Am J Respir Cell Mol Biol. 2008 Mar;38(3):251-5. doi: 10.1165/rcmb.2007-0331TR. Epub 2007 Oct 11. Am J Respir Cell Mol Biol. 2008. PMID: 17932373 Review.

4

Subversion of a lysosomal pathway regulating neutrophil apoptosis by a major bacterial toxin, pyocyanin.

Prince LR, Bianchi SM, Vaughan KM, Bewley MA, Marriott HM, Walmsley SR, Taylor GW, Buttle DJ, Sabroe I, Dockrell DH, Whyte MK. Prince LR, et al. Among authors: walmsley sr. J Immunol. 2008 Mar 1;180(5):3502-11. doi: 10.4049/jimmunol.180.5.3502. J Immunol. 2008. PMID: 18292577 Free PMC article.

5

Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function.

Walmsley SR, Chilvers ER, Whyte MK. Walmsley SR, et al. Arthritis Res Ther. 2009;11(2):219. doi: 10.1186/ar2632. Epub 2009 Apr 21. Arthritis Res Ther. 2009. PMID: 19435530 Free PMC article. Review.

6

Distinct cell death programs in monocytes regulate innate responses following challenge with common causes of invasive bacterial disease.

Webster SJ, Daigneault M, Bewley MA, Preston JA, Marriott HM, Walmsley SR, Read RC, Whyte MK, Dockrell DH. Webster SJ, et al. Among authors: walmsley sr. J Immunol. 2010 Sep 1;185(5):2968-79. doi: 10.4049/jimmunol.1000805. Epub 2010 Jul 23. J Immunol. 2010. PMID: 20656927 Free PMC article.

7

Hypoxia selectively inhibits respiratory burst activity and killing of Staphylococcus aureus in human neutrophils.

McGovern NN, Cowburn AS, Porter L, Walmsley SR, Summers C, Thompson AAR, Anwar S, Willcocks LC, Whyte MKB, Condliffe AM, Chilvers ER. McGovern NN, et al. Among authors: walmsley sr. J Immunol. 2011 Jan 1;186(1):453-463. doi: 10.4049/jimmunol.1002213. Epub 2010 Dec 6. J Immunol. 2011. PMID: 21135168 Free PMC article.

8

Prolyl hydroxylase 3 (PHD3) is essential for hypoxic regulation of neutrophilic inflammation in humans and mice.

Walmsley SR, Chilvers ER, Thompson AA, Vaughan K, Marriott HM, Parker LC, Shaw G, Parmar S, Schneider M, Sabroe I, Dockrell DH, Milo M, Taylor CT, Johnson RS, Pugh CW, Ratcliffe PJ, Maxwell PH, Carmeliet P, Whyte MK. Walmsley SR, et al. J Clin Invest. 2011 Mar;121(3):1053-63. doi: 10.1172/JCI43273. Epub 2011 Feb 7. J Clin Invest. 2011. PMID: 21317538 Free PMC article.

9

Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model.

Elks PM, van Eeden FJ, Dixon G, Wang X, Reyes-Aldasoro CC, Ingham PW, Whyte MK, Walmsley SR, Renshaw SA. Elks PM, et al. Among authors: walmsley sr. Blood. 2011 Jul 21;118(3):712-22. doi: 10.1182/blood-2010-12-324186. Epub 2011 May 9. Blood. 2011. PMID: 21555741 Free article.

10

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis.

McGrath EE, Lawrie A, Marriott HM, Mercer P, Cross SS, Arnold N, Singleton V, Thompson AA, Walmsley SR, Renshaw SA, Sabroe I, Chambers RC, Dockrell DH, Whyte MK. McGrath EE, et al. Among authors: walmsley sr. Thorax. 2012 Sep;67(9):796-803. doi: 10.1136/thoraxjnl-2011-200863. Epub 2012 Apr 11. Thorax. 2012. PMID: 22496351 Free PMC article.

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