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Development of a minimal saponin vaccine adjuvant based on QS-21.
Fernández-Tejada A, Chea EK, George C, Pillarsetty N, Gardner JR, Livingston PO, Ragupathi G, Lewis JS, Tan DS, Gin DY. Fernández-Tejada A, et al. Among authors: george c. Nat Chem. 2014 Jul;6(7):635-43. doi: 10.1038/nchem.1963. Epub 2014 Jun 1. Nat Chem. 2014. PMID: 24950335 Free PMC article.
Immunization with N-propionyl polysialic acid-KLH conjugate in patients with small cell lung cancer is safe and induces IgM antibodies reactive with SCLC cells and bactericidal against group B meningococci.
Krug LM, Ragupathi G, Hood C, George C, Hong F, Shen R, Abrey L, Jennings HJ, Kris MG, Livingston PO. Krug LM, et al. Among authors: george c. Cancer Immunol Immunother. 2012 Jan;61(1):9-18. doi: 10.1007/s00262-011-1083-6. Epub 2011 Aug 3. Cancer Immunol Immunother. 2012. PMID: 21811785 Free PMC article. Clinical Trial.
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