Jiménez-Barbero J - Search Results

1

Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities.

Walkowicz WE, Fernández-Tejada A, George C, Corzana F, Jiménez-Barbero J, Ragupathi G, Tan DS, Gin DY. Walkowicz WE, et al. Chem Sci. 2016 Mar;7(3):2371-2380. doi: 10.1039/C5SC02978C. Epub 2016 Jan 15. Chem Sci. 2016. PMID: 27014435 Free PMC article.

2

Limited flexibility of lactose detected from residual dipolar couplings using molecular dynamics simulations and steric alignment methods.

Martín-Pastor M, Canales A, Corzana F, Asensio JL, Jiménez-Barbero J. Martín-Pastor M, et al. J Am Chem Soc. 2005 Mar 16;127(10):3589-95. doi: 10.1021/ja043445m. J Am Chem Soc. 2005. PMID: 15755180

3

A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.

Asensio JL, Hidalgo A, Bastida A, Torrado M, Corzana F, Chiara JL, García-Junceda E, Cañada J, Jiménez-Barbero J. Asensio JL, et al. J Am Chem Soc. 2005 Jun 15;127(23):8278-9. doi: 10.1021/ja051722z. J Am Chem Soc. 2005. PMID: 15941249 Free article.

4

Molecular recognition of aminoglycoside antibiotics by bacterial defence proteins: NMR study of the structural and conformational features of streptomycin inactivation by Bacillus subtilis aminoglycoside-6-adenyl transferase.

Corzana F, Cuesta I, Bastida A, Hidalgo A, Latorre M, González C, García-Junceda E, Jiménez-Barbero J, Asensio JL. Corzana F, et al. Chemistry. 2005 Aug 19;11(17):5102-13. doi: 10.1002/chem.200400941. Chemistry. 2005. PMID: 15984036

5

Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance.

Bastida A, Hidalgo A, Chiara JL, Torrado M, Corzana F, Pérez-Cañadillas JM, Groves P, Garcia-Junceda E, Gonzalez C, Jimenez-Barbero J, Asensio JL. Bastida A, et al. J Am Chem Soc. 2006 Jan 11;128(1):100-16. doi: 10.1021/ja0543144. J Am Chem Soc. 2006. PMID: 16390137 Free article.

6

Effect of beta-O-glucosylation on L-Ser and L-Thr diamides: a bias toward alpha-helical conformations.

Corzana F, Busto JH, Engelsen SB, Jiménez-Barbero J, Asensio JL, Peregrina JM, Avenoza A. Corzana F, et al. Chemistry. 2006 Oct 16;12(30):7864-71. doi: 10.1002/chem.200600128. Chemistry. 2006. PMID: 16850514

7

New insights into alpha-GalNAc-Ser motif: influence of hydrogen bonding versus solvent interactions on the preferred conformation.

Corzana F, Busto JH, Jiménez-Osés G, Asensio JL, Jiménez-Barbero J, Peregrina JM, Avenoza A. Corzana F, et al. J Am Chem Soc. 2006 Nov 15;128(45):14640-8. doi: 10.1021/ja064539u. J Am Chem Soc. 2006. PMID: 17090050

8

A simple NMR analysis of the protonation equilibrium that accompanies aminoglycoside recognition: dramatic alterations in the neomycin-B protonation state upon binding to a 23-mer RNA aptamer.

Freire F, Cuesta I, Corzana F, Revuelta J, González C, Hricovini M, Bastida A, Jiménez-Barbero J, Asensio JL. Freire F, et al. Chem Commun (Camb). 2007 Jan 14;(2):174-6. doi: 10.1039/b611597g. Epub 2006 Oct 23. Chem Commun (Camb). 2007. PMID: 17180237

9

The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: implications for RNA recognition.

Corzana F, Cuesta I, Freire F, Revuelta J, Torrado M, Bastida A, Jiménez-Barbero J, Asensio JL. Corzana F, et al. J Am Chem Soc. 2007 Mar 14;129(10):2849-65. doi: 10.1021/ja066348x. Epub 2007 Feb 14. J Am Chem Soc. 2007. PMID: 17298063

10

Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell.

Corzana F, Busto JH, Jiménez-Osés G, García de Luis M, Asensio JL, Jiménez-Barbero J, Peregrina JM, Avenoza A. Corzana F, et al. J Am Chem Soc. 2007 Aug 1;129(30):9458-67. doi: 10.1021/ja072181b. Epub 2007 Jul 7. J Am Chem Soc. 2007. PMID: 17616194

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