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A blood RNA signature for tuberculosis disease risk: a prospective cohort study.
Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff THM, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SHE, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups. Zak DE, et al. Lancet. 2016 Jun 4;387(10035):2312-2322. doi: 10.1016/S0140-6736(15)01316-1. Epub 2016 Mar 24. Lancet. 2016. PMID: 27017310 Free PMC article.
Qualification of a whole blood intracellular cytokine staining assay to measure mycobacteria-specific CD4 and CD8 T cell immunity by flow cytometry.
Kagina BM, Mansoor N, Kpamegan EP, Penn-Nicholson A, Nemes E, Smit E, Gelderbloem S, Soares AP, Abel B, Keyser A, Sidibana M, Hughes JE, Kaplan G, Hussey GD, Hanekom WA, Scriba TJ. Kagina BM, et al. J Immunol Methods. 2015 Feb;417:22-33. doi: 10.1016/j.jim.2014.12.003. Epub 2014 Dec 16. J Immunol Methods. 2015. PMID: 25523923 Free PMC article.
Safety and immunogenicity of candidate vaccine M72/AS01E in adolescents in a TB endemic setting.
Penn-Nicholson A, Geldenhuys H, Burny W, van der Most R, Day CL, Jongert E, Moris P, Hatherill M, Ofori-Anyinam O, Hanekom W; Vaccine Study Team; Bollaerts A, Demoitie MA, Kany Luabeya AK, De Ruymaeker E, Tameris M, Lapierre D, Scriba TJ. Penn-Nicholson A, et al. Vaccine. 2015 Jul 31;33(32):4025-34. doi: 10.1016/j.vaccine.2015.05.088. Epub 2015 Jun 10. Vaccine. 2015. PMID: 26072017 Free PMC article. Clinical Trial.
T-cell activation is an immune correlate of risk in BCG vaccinated infants.
Fletcher HA, Snowden MA, Landry B, Rida W, Satti I, Harris SA, Matsumiya M, Tanner R, O'Shea MK, Dheenadhayalan V, Bogardus L, Stockdale L, Marsay L, Chomka A, Harrington-Kandt R, Manjaly-Thomas ZR, Naranbhai V, Stylianou E, Darboe F, Penn-Nicholson A, Nemes E, Hatherill M, Hussey G, Mahomed H, Tameris M, McClain JB, Evans TG, Hanekom WA, Scriba TJ, McShane H. Fletcher HA, et al. Nat Commun. 2016 Apr 12;7:11290. doi: 10.1038/ncomms11290. Nat Commun. 2016. PMID: 27068708 Free PMC article. Clinical Trial.
Predicting tuberculosis risk - Authors' reply.
Zak D, Scriba TJ, Hatherill M, Penn-Nicholson A, Hanekom W. Zak D, et al. Lancet. 2016 Nov 5;388(10057):2233-2234. doi: 10.1016/S0140-6736(16)31653-1. Lancet. 2016. PMID: 27825498 No abstract available.
A novel blood test for tuberculosis prevention and treatment.
Penn-Nicholson A, Scriba TJ, Hatherill M, White RG, Sumner T. Penn-Nicholson A, et al. S Afr Med J. 2016 Dec 21;107(1):4-5. doi: 10.7196/SAMJ.2016.v107.i1.12230. S Afr Med J. 2016. PMID: 28112082 No abstract available.
Antigen Availability Shapes T Cell Differentiation and Function during Tuberculosis.
Moguche AO, Musvosvi M, Penn-Nicholson A, Plumlee CR, Mearns H, Geldenhuys H, Smit E, Abrahams D, Rozot V, Dintwe O, Hoff ST, Kromann I, Ruhwald M, Bang P, Larson RP, Shafiani S, Ma S, Sherman DR, Sette A, Lindestam Arlehamn CS, McKinney DM, Maecker H, Hanekom WA, Hatherill M, Andersen P, Scriba TJ, Urdahl KB. Moguche AO, et al. Cell Host Microbe. 2017 Jun 14;21(6):695-706.e5. doi: 10.1016/j.chom.2017.05.012. Cell Host Microbe. 2017. PMID: 28618268 Free PMC article. Clinical Trial.
The Cross-Species Mycobacterial Growth Inhibition Assay (MGIA) Project, 2010-2014.
Brennan MJ, Tanner R, Morris S, Scriba TJ, Achkar JM, Zelmer A, Hokey DA, Izzo A, Sharpe S, Williams A, Penn-Nicholson A, Erasmus M, Stylianou E, Hoft DF, McShane H, Fletcher HA. Brennan MJ, et al. Clin Vaccine Immunol. 2017 Sep 5;24(9):e00142-17. doi: 10.1128/CVI.00142-17. Print 2017 Sep. Clin Vaccine Immunol. 2017. PMID: 28701467 Free PMC article. Review.
84 results