Brown H - Search Results

1

Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.

Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Okerberg ES, et al. Among authors: brown h. PLoS One. 2016 Mar 31;11(3):e0152934. doi: 10.1371/journal.pone.0152934. eCollection 2016. PLoS One. 2016. PMID: 27031502 Free PMC article.

2

Monitoring native p38α:MK2/3 complexes via trans delivery of an ATP acyl phosphate probe.

Okerberg ES, Brown HE, Minimo L, Alemayehu S, Rosenblum J, Patricelli M, Nomanbhoy T, Kozarich JW. Okerberg ES, et al. J Am Chem Soc. 2014 Mar 26;136(12):4664-9. doi: 10.1021/ja4129907. Epub 2014 Mar 17. J Am Chem Soc. 2014. PMID: 24601623

3

In situ kinase profiling reveals functionally relevant properties of native kinases.

Patricelli MP, Nomanbhoy TK, Wu J, Brown H, Zhou D, Zhang J, Jagannathan S, Aban A, Okerberg E, Herring C, Nordin B, Weissig H, Yang Q, Lee JD, Gray NS, Kozarich JW. Patricelli MP, et al. Among authors: brown h. Chem Biol. 2011 Jun 24;18(6):699-710. doi: 10.1016/j.chembiol.2011.04.011. Chem Biol. 2011. PMID: 21700206 Free PMC article.

4

Profiling native kinases by immuno-assisted activity-based profiling.

Okerberg E, Shih A, Brown H, Alemayehu S, Aban A, Nomanbhoy TK. Okerberg E, et al. Among authors: brown h. Curr Protoc Chem Biol. 2013;5(3):213-26. doi: 10.1002/9780470559277.ch130084. Curr Protoc Chem Biol. 2013. PMID: 24391084

5

Chemoproteomic Evaluation of Target Engagement by the Cyclin-Dependent Kinase 4 and 6 Inhibitor Palbociclib Correlates with Cancer Cell Response.

Nomanbhoy TK, Sharma G, Brown H, Wu J, Aban A, Vogeti S, Alemayehu S, Sykes M, Rosenblum JS, Kozarich JW. Nomanbhoy TK, et al. Among authors: brown h. Biochemistry. 2016 Sep 27;55(38):5434-41. doi: 10.1021/acs.biochem.6b00629. Epub 2016 Sep 13. Biochemistry. 2016. PMID: 27571378

6

Correction: Identification of a Tumor Specific, Active-Site Mutation in Casein Kinase 1α by Chemical Proteomics.

Okerberg ES, Hainley A, Brown H, Aban A, Alemayehu S, Shih A, Wu J, Patricelli MP, Kozarich JW, Nomanbhoy T, Rosenblum JS. Okerberg ES, et al. Among authors: brown h. PLoS One. 2017 Feb 15;12(2):e0172649. doi: 10.1371/journal.pone.0172649. eCollection 2017. PLoS One. 2017. PMID: 28199383 Free PMC article.

7

Synthesis and structure-activity relationship of (1-halo-2-naphthyl) carbamate-based inhibitors of KIAA1363 (NCEH1/AADACL1).

Shreder KR, Lin EC, Wu J, Cajica J, Amantea CM, Hu Y, Okerberg E, Brown HE, Pham LM, Chung de M, Fraser AS, McGee E, Rosenblum JS, Kozarich JW. Shreder KR, et al. Bioorg Med Chem Lett. 2012 Sep 1;22(17):5748-51. doi: 10.1016/j.bmcl.2012.05.102. Epub 2012 Jun 6. Bioorg Med Chem Lett. 2012. PMID: 22877630

8

Amides of xanthurenic acid as zinc-dependent inhibitors of Lp-PLA(2).

Lin EC, Hu Y, Amantea CM, Pham LM, Cajica J, Okerberg E, Brown HE, Fraser A, Du L, Kohno Y, Ishiyama J, Kozarich JW, Shreder KR. Lin EC, et al. Bioorg Med Chem Lett. 2012 Jan 15;22(2):868-71. doi: 10.1016/j.bmcl.2011.12.045. Epub 2011 Dec 13. Bioorg Med Chem Lett. 2012. PMID: 22217870

9

Amides of 4-hydroxy-8-methanesulfonylamino-quinoline-2-carboxylic acid as zinc-dependent inhibitors of Lp-PLA₂.

Hu Y, Lin EC, Pham LM, Cajica J, Amantea CM, Okerberg E, Brown HE, Fraser A, Du L, Kohno Y, Ishiyama J, Kozarich JW, Shreder KR. Hu Y, et al. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1553-6. doi: 10.1016/j.bmcl.2012.11.048. Epub 2012 Dec 8. Bioorg Med Chem Lett. 2013. PMID: 23333209

10

ATP Acyl Phosphate Reactivity Reveals Native Conformations of Hsp90 Paralogs and Inhibitor Target Engagement.

Nordin BE, Liu Y, Aban A, Brown HE, Wu J, Hainley AK, Rosenblum JS, Nomanbhoy TK, Kozarich JW. Nordin BE, et al. Biochemistry. 2015 May 19;54(19):3024-36. doi: 10.1021/acs.biochem.5b00148. Biochemistry. 2015. PMID: 25905789

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