O'Rourke DM - Search Results

1

c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma.

Huang M, Liu T, Ma P, Mitteer RA Jr, Zhang Z, Kim HJ, Yeo E, Zhang D, Cai P, Li C, Zhang L, Zhao B, Roccograndi L, O'Rourke DM, Dahmane N, Gong Y, Koumenis C, Fan Y. Huang M, et al. J Clin Invest. 2016 May 2;126(5):1801-14. doi: 10.1172/JCI84876. Epub 2016 Apr 4. J Clin Invest. 2016. PMID: 27043280 Free PMC article.

2

Imaging patterns predict patient survival and molecular subtype in glioblastoma via machine learning techniques.

Macyszyn L, Akbari H, Pisapia JM, Da X, Attiah M, Pigrish V, Bi Y, Pal S, Davuluri RV, Roccograndi L, Dahmane N, Martinez-Lage M, Biros G, Wolf RL, Bilello M, O'Rourke DM, Davatzikos C. Macyszyn L, et al. Neuro Oncol. 2016 Mar;18(3):417-25. doi: 10.1093/neuonc/nov127. Epub 2015 Jul 16. Neuro Oncol. 2016. PMID: 26188015 Free PMC article.

3

In Vivo Detection of EGFRvIII in Glioblastoma via Perfusion Magnetic Resonance Imaging Signature Consistent with Deep Peritumoral Infiltration: The φ-Index.

Bakas S, Akbari H, Pisapia J, Martinez-Lage M, Rozycki M, Rathore S, Dahmane N, O'Rourke DM, Davatzikos C. Bakas S, et al. Clin Cancer Res. 2017 Aug 15;23(16):4724-4734. doi: 10.1158/1078-0432.CCR-16-1871. Epub 2017 Apr 20. Clin Cancer Res. 2017. PMID: 28428190 Free PMC article.

4

SHP2 regulates proliferation and tumorigenicity of glioma stem cells.

Roccograndi L, Binder ZA, Zhang L, Aceto N, Zhang Z, Bentires-Alj M, Nakano I, Dahmane N, O'Rourke DM. Roccograndi L, et al. J Neurooncol. 2017 Dec;135(3):487-496. doi: 10.1007/s11060-017-2610-x. Epub 2017 Aug 29. J Neurooncol. 2017. PMID: 28852935

5

Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2α.

Wang Q, He Z, Huang M, Liu T, Wang Y, Xu H, Duan H, Ma P, Zhang L, Zamvil SS, Hidalgo J, Zhang Z, O'Rourke DM, Dahmane N, Brem S, Mou Y, Gong Y, Fan Y. Wang Q, et al. Nat Commun. 2018 Feb 8;9(1):559. doi: 10.1038/s41467-018-03050-0. Nat Commun. 2018. PMID: 29422647 Free PMC article.

6

PDGF-mediated mesenchymal transformation renders endothelial resistance to anti-VEGF treatment in glioblastoma.

Liu T, Ma W, Xu H, Huang M, Zhang D, He Z, Zhang L, Brem S, O'Rourke DM, Gong Y, Mou Y, Zhang Z, Fan Y. Liu T, et al. Nat Commun. 2018 Aug 27;9(1):3439. doi: 10.1038/s41467-018-05982-z. Nat Commun. 2018. PMID: 30150753 Free PMC article.

7

Circulating Glioma Cells Exhibit Stem Cell-like Properties.

Liu T, Xu H, Huang M, Ma W, Saxena D, Lustig RA, Alonso-Basanta M, Zhang Z, O'Rourke DM, Zhang L, Gong Y, Kao GD, Dorsey JF, Fan Y. Liu T, et al. Cancer Res. 2018 Dec 1;78(23):6632-6642. doi: 10.1158/0008-5472.CAN-18-0650. Epub 2018 Oct 15. Cancer Res. 2018. PMID: 30322863 Free PMC article.

8

Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma.

Huang M, Zhang D, Wu JY, Xing K, Yeo E, Li C, Zhang L, Holland E, Yao L, Qin L, Binder ZA, O'Rourke DM, Brem S, Koumenis C, Gong Y, Fan Y. Huang M, et al. Sci Transl Med. 2020 Feb 26;12(532):eaay7522. doi: 10.1126/scitranslmed.aay7522. Sci Transl Med. 2020. PMID: 32102932 Free PMC article.

9

Targeting PAK4 to reprogram the vascular microenvironment and improve CAR-T immunotherapy for glioblastoma.

Ma W, Wang Y, Zhang R, Yang F, Zhang D, Huang M, Zhang L, Dorsey JF, Binder ZA, O'Rourke DM, Fraietta JA, Gong Y, Fan Y. Ma W, et al. Nat Cancer. 2021 Jan;2(1):83-97. doi: 10.1038/s43018-020-00147-8. Epub 2020 Nov 30. Nat Cancer. 2021. PMID: 35121889 Free PMC article.

10

In vivo evaluation of EGFRvIII mutation in primary glioblastoma patients via complex multiparametric MRI signature.

Akbari H, Bakas S, Pisapia JM, Nasrallah MP, Rozycki M, Martinez-Lage M, Morrissette JJD, Dahmane N, O'Rourke DM, Davatzikos C. Akbari H, et al. Neuro Oncol. 2018 Jul 5;20(8):1068-1079. doi: 10.1093/neuonc/noy033. Neuro Oncol. 2018. PMID: 29617843 Free PMC article.

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