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Increased lethality and defective pulmonary clearance of Streptococcus pneumoniae in microsomal prostaglandin E synthase-1-knockout mice.
Dolan JM, Weinberg JB, O'Brien E, Abashian A, Procario MC, Aronoff DM, Crofford LJ, Peters-Golden M, Ward L, Mancuso P. Dolan JM, et al. Among authors: crofford lj. Am J Physiol Lung Cell Mol Physiol. 2016 Jun 1;310(11):L1111-20. doi: 10.1152/ajplung.00220.2015. Epub 2016 Apr 8. Am J Physiol Lung Cell Mol Physiol. 2016. PMID: 27059285 Free PMC article.
Defective generation of a humoral immune response is associated with a reduced incidence and severity of collagen-induced arthritis in microsomal prostaglandin E synthase-1 null mice.
Kojima F, Kapoor M, Yang L, Fleishaker EL, Ward MR, Monrad SU, Kottangada PC, Pace CQ, Clark JA, Woodward JG, Crofford LJ. Kojima F, et al. Among authors: crofford lj. J Immunol. 2008 Jun 15;180(12):8361-8. doi: 10.4049/jimmunol.180.12.8361. J Immunol. 2008. PMID: 18523303 Free PMC article.
Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2.
Mason KL, Rogers LM, Soares EM, Bani-Hashemi T, Erb Downward J, Agnew D, Peters-Golden M, Weinberg JB, Crofford LJ, Aronoff DM. Mason KL, et al. Among authors: crofford lj. J Immunol. 2013 Sep 1;191(5):2457-65. doi: 10.4049/jimmunol.1300786. Epub 2013 Aug 2. J Immunol. 2013. PMID: 23913961 Free PMC article.
When Enough Is Enough: Decision Criteria for Moving a Known Drug into Clinical Testing for a New Indication in the Absence of Preclinical Efficacy Data.
Pulley JM, Jerome RN, Zaleski NM, Shirey-Rice JK, Pruijssers AJ, Lavieri RR, Chettiar SN, Naylor HM, Aronoff DM, Edwards DA, Niswender CM, Dugan LL, Crofford LJ, Bernard GR, Holroyd KJ. Pulley JM, et al. Among authors: crofford lj. Assay Drug Dev Technol. 2017 Dec;15(8):354-361. doi: 10.1089/adt.2017.821. Epub 2017 Dec 1. Assay Drug Dev Technol. 2017. PMID: 29193979 Free PMC article.
Nonsteroidal Anti-inflammatory Drugs Alter the Microbiota and Exacerbate Clostridium difficile Colitis while Dysregulating the Inflammatory Response.
Maseda D, Zackular JP, Trindade B, Kirk L, Roxas JL, Rogers LM, Washington MK, Du L, Koyama T, Viswanathan VK, Vedantam G, Schloss PD, Crofford LJ, Skaar EP, Aronoff DM. Maseda D, et al. Among authors: crofford lj. mBio. 2019 Jan 8;10(1):e02282-18. doi: 10.1128/mBio.02282-18. mBio. 2019. PMID: 30622186 Free PMC article.
Human and Machine Intelligence Together Drive Drug Repurposing in Rare Diseases.
Challa AP, Zaleski NM, Jerome RN, Lavieri RR, Shirey-Rice JK, Barnado A, Lindsell CJ, Aronoff DM, Crofford LJ, Harris RC, Alp Ikizler T, Mayer IA, Holroyd KJ, Pulley JM. Challa AP, et al. Among authors: crofford lj. Front Genet. 2021 Jul 28;12:707836. doi: 10.3389/fgene.2021.707836. eCollection 2021. Front Genet. 2021. PMID: 34394194 Free PMC article.
280 results