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A dominant TRPV4 variant underlies osteochondrodysplasia in Scottish fold cats.
Gandolfi B, Alamri S, Darby WG, Adhikari B, Lattimer JC, Malik R, Wade CM, Lyons LA, Cheng J, Bateman JF, McIntyre P, Lamandé SR, Haase B. Gandolfi B, et al. Among authors: mcintyre p. Osteoarthritis Cartilage. 2016 Aug;24(8):1441-50. doi: 10.1016/j.joca.2016.03.019. Epub 2016 Apr 6. Osteoarthritis Cartilage. 2016. PMID: 27063440 Free article.
Modulation of TRPV4 by diverse mechanisms.
Darby WG, Grace MS, Baratchi S, McIntyre P. Darby WG, et al. Among authors: mcintyre p. Int J Biochem Cell Biol. 2016 Sep;78:217-228. doi: 10.1016/j.biocel.2016.07.012. Epub 2016 Jul 15. Int J Biochem Cell Biol. 2016. PMID: 27425399 Review.
Mutations in TRPV4 cause an inherited arthropathy of hands and feet.
Lamandé SR, Yuan Y, Gresshoff IL, Rowley L, Belluoccio D, Kaluarachchi K, Little CB, Botzenhart E, Zerres K, Amor DJ, Cole WG, Savarirayan R, McIntyre P, Bateman JF. Lamandé SR, et al. Among authors: mcintyre p. Nat Genet. 2011 Oct 2;43(11):1142-6. doi: 10.1038/ng.945. Nat Genet. 2011. PMID: 21964574
Marine Bile Natural Products as Agonists of the TGR5 Receptor.
Halkias C, Darby WG, Feltis BN, McIntyre P, Macrides TA, Wright PFA. Halkias C, et al. Among authors: mcintyre p. J Nat Prod. 2021 May 28;84(5):1507-1514. doi: 10.1021/acs.jnatprod.0c01327. Epub 2021 Apr 27. J Nat Prod. 2021. PMID: 33904732
The transient receptor potential vanilloid 4 (TRPV4) ion channel mediates protease activated receptor 1 (PAR1)-induced vascular hyperpermeability.
Peng S, Grace MS, Gondin AB, Retamal JS, Dill L, Darby W, Bunnett NW, Abogadie FC, Carbone SE, Tigani T, Davis TP, Poole DP, Veldhuis NA, McIntyre P. Peng S, et al. Among authors: mcintyre p. Lab Invest. 2020 Aug;100(8):1057-1067. doi: 10.1038/s41374-020-0430-7. Epub 2020 Apr 27. Lab Invest. 2020. PMID: 32341518 Free PMC article.
1,118 results