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The enhancer landscape predetermines the skeletal regeneration capacity of stromal cells.
Hochmann S, Ou K, Poupardin R, Mittermeir M, Textor M, Ali S, Wolf M, Ellinghaus A, Jacobi D, Elmiger JAJ, Donsante S, Riminucci M, Schäfer R, Kornak U, Klein O, Schallmoser K, Schmidt-Bleek K, Duda GN, Polansky JK, Geissler S, Strunk D. Hochmann S, et al. Among authors: polansky jk. Sci Transl Med. 2023 Mar 22;15(688):eabm7477. doi: 10.1126/scitranslmed.abm7477. Epub 2023 Mar 22. Sci Transl Med. 2023. PMID: 36947595
Epigenetic control of the foxp3 locus in regulatory T cells.
Floess S, Freyer J, Siewert C, Baron U, Olek S, Polansky J, Schlawe K, Chang HD, Bopp T, Schmitt E, Klein-Hessling S, Serfling E, Hamann A, Huehn J. Floess S, et al. PLoS Biol. 2007 Feb;5(2):e38. doi: 10.1371/journal.pbio.0050038. PLoS Biol. 2007. PMID: 17298177 Free PMC article.
DNA methylation controls Foxp3 gene expression.
Polansky JK, Kretschmer K, Freyer J, Floess S, Garbe A, Baron U, Olek S, Hamann A, von Boehmer H, Huehn J. Polansky JK, et al. Eur J Immunol. 2008 Jun;38(6):1654-63. doi: 10.1002/eji.200838105. Eur J Immunol. 2008. PMID: 18493985 Free article.
Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus.
Toker A, Engelbert D, Garg G, Polansky JK, Floess S, Miyao T, Baron U, Düber S, Geffers R, Giehr P, Schallenberg S, Kretschmer K, Olek S, Walter J, Weiss S, Hori S, Hamann A, Huehn J. Toker A, et al. Among authors: polansky jk. J Immunol. 2013 Apr 1;190(7):3180-8. doi: 10.4049/jimmunol.1203473. Epub 2013 Feb 18. J Immunol. 2013. PMID: 23420886
28 results