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Page 1
Alkylating Agent-Induced NRF2 Blocks Endoplasmic Reticulum Stress-Mediated Apoptosis via Control of Glutathione Pools and Protein Thiol Homeostasis.
Zanotto-Filho A, Masamsetti VP, Loranc E, Tonapi SS, Gorthi A, Bernard X, Gonçalves RM, Moreira JC, Chen Y, Bishop AJ. Zanotto-Filho A, et al. Among authors: loranc e. Mol Cancer Ther. 2016 Dec;15(12):3000-3014. doi: 10.1158/1535-7163.MCT-16-0271. Epub 2016 Sep 16. Mol Cancer Ther. 2016. PMID: 27638861 Free PMC article.
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.
Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, Bishop AJR. Gorthi A, et al. Among authors: loranc e. Nature. 2018 Mar 15;555(7696):387-391. doi: 10.1038/nature25748. Epub 2018 Mar 7. Nature. 2018. PMID: 29513652 Free PMC article.
Sorafenib improves alkylating therapy by blocking induced inflammation, invasion and angiogenesis in breast cancer cells.
Zanotto-Filho A, Rajamanickam S, Loranc E, Masamsetti VP, Gorthi A, Romero JC, Tonapi S, Gonçalves RM, Reddick RL, Benavides R, Kuhn J, Chen Y, Bishop AJR. Zanotto-Filho A, et al. Among authors: loranc e. Cancer Lett. 2018 Jul 1;425:101-115. doi: 10.1016/j.canlet.2018.03.037. Epub 2018 Mar 30. Cancer Lett. 2018. PMID: 29608984 Free PMC article.
TATDN2 resolution of R-loops is required for survival of BRCA1-mutant cancer cells.
Jaiswal AS, Dutta A, Srinivasan G, Yuan Y, Zhou D, Shaheen M, Sadideen DT, Kirby A, Williamson EA, Gupta YK, Olsen SK, Xu M, Loranc E, Mukhopadhyay P, Pertsemlidis A, Bishop AJR, Sung P, Nickoloff JA, Hromas R. Jaiswal AS, et al. Among authors: loranc e. Nucleic Acids Res. 2023 Dec 11;51(22):12224-12241. doi: 10.1093/nar/gkad952. Nucleic Acids Res. 2023. PMID: 37953292 Free PMC article.
ATM phosphorylation of CD98HC increases antiporter membrane localization and prevents chronic toxic glutamate accumulation in Ataxia telangiectasia.
Bishop A, Romero JC, Tonapi S, Parihar M, Loranc E, Miller H, Lawrence L, Bassani N, Robledo D, Cao L, Nie J, Kanda K, Stoja A, Garcia N, Gorthi A, Stoveken B, Lane A, Fan T, Cassel T, Zha S, Musi N. Bishop A, et al. Among authors: loranc e. Res Sq [Preprint]. 2024 Sep 5:rs.3.rs-4947457. doi: 10.21203/rs.3.rs-4947457/v1. Res Sq. 2024. PMID: 39281865 Free PMC article. Preprint.