Chigaev A - Search Results

1

Cyclic AMP efflux inhibitors as potential therapeutic agents for leukemia.

Perez DR, Smagley Y, Garcia M, Carter MB, Evangelisti A, Matlawska-Wasowska K, Winter SS, Sklar LA, Chigaev A. Perez DR, et al. Among authors: chigaev a. Oncotarget. 2016 Jun 7;7(23):33960-82. doi: 10.18632/oncotarget.8986. Oncotarget. 2016. PMID: 27129155 Free PMC article.

2

A High-Throughput Flow Cytometry Assay for Identification of Inhibitors of 3',5'-Cyclic Adenosine Monophosphate Efflux.

Perez D, Simons PC, Smagley Y, Sklar LA, Chigaev A. Perez D, et al. Among authors: chigaev a. Methods Mol Biol. 2016;1439:227-44. doi: 10.1007/978-1-4939-3673-1_15. Methods Mol Biol. 2016. PMID: 27316999 Free PMC article.

3

High-Throughput Flow Cytometry Identifies Small-Molecule Inhibitors for Drug Repurposing in T-ALL.

Perez DR, Nickl CK, Waller A, Delgado-Martin C, Woods T, Sharma ND, Hermiston ML, Loh ML, Hunger SP, Winter SS, Chigaev A, Edwards B, Sklar LA, Matlawska-Wasowska K. Perez DR, et al. Among authors: chigaev a. SLAS Discov. 2018 Aug;23(7):732-741. doi: 10.1177/2472555218774248. Epub 2018 May 10. SLAS Discov. 2018. PMID: 29746793 Free PMC article.

4

Drug repurposing for targeting cyclic nucleotide transporters in acute leukemias - A missed opportunity.

Perez DR, Sklar LA, Chigaev A, Matlawska-Wasowska K. Perez DR, et al. Among authors: chigaev a. Semin Cancer Biol. 2021 Jan;68:199-208. doi: 10.1016/j.semcancer.2020.02.004. Epub 2020 Feb 7. Semin Cancer Biol. 2021. PMID: 32044470 Free PMC article. Review.

5

Regulation of cell adhesion by affinity and conformational unbending of alpha4beta1 integrin.

Chigaev A, Waller A, Zwartz GJ, Buranda T, Sklar LA. Chigaev A, et al. J Immunol. 2007 Jun 1;178(11):6828-39. doi: 10.4049/jimmunol.178.11.6828. J Immunol. 2007. PMID: 17513731

6

Galphas-coupled receptor signaling actively down-regulates alpha4beta1-integrin affinity: a possible mechanism for cell de-adhesion.

Chigaev A, Waller A, Amit O, Sklar LA. Chigaev A, et al. BMC Immunol. 2008 Jun 5;9:26. doi: 10.1186/1471-2172-9-26. BMC Immunol. 2008. PMID: 18534032 Free PMC article.

7

Discovery of very late antigen-4 (VLA-4, alpha4beta1 integrin) allosteric antagonists.

Chigaev A, Wu Y, Williams DB, Smagley Y, Sklar LA. Chigaev A, et al. J Biol Chem. 2011 Feb 18;286(7):5455-63. doi: 10.1074/jbc.M110.162636. Epub 2010 Dec 3. J Biol Chem. 2011. PMID: 21131351 Free PMC article.

8

Real-time analysis of the inside-out regulation of lymphocyte function-associated antigen-1 revealed similarities to and differences from very late antigen-4.

Chigaev A, Smagley Y, Zhang Y, Waller A, Haynes MK, Amit O, Wang W, Larson RS, Sklar LA. Chigaev A, et al. J Biol Chem. 2011 Jun 10;286(23):20375-86. doi: 10.1074/jbc.M110.206185. Epub 2011 Apr 22. J Biol Chem. 2011. PMID: 21515675 Free PMC article.

9

Nitric oxide/cGMP pathway signaling actively down-regulates α4β1-integrin affinity: an unexpected mechanism for inducing cell de-adhesion.

Chigaev A, Smagley Y, Sklar LA. Chigaev A, et al. BMC Immunol. 2011 May 17;12:28. doi: 10.1186/1471-2172-12-28. BMC Immunol. 2011. PMID: 21586157 Free PMC article.

10

Overview: assays for studying integrin-dependent cell adhesion.

Chigaev A, Sklar LA. Chigaev A, et al. Methods Mol Biol. 2012;757:3-14. doi: 10.1007/978-1-61779-166-6_1. Methods Mol Biol. 2012. PMID: 21909902 Free PMC article. Review.

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