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Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice.
Keller A, Westenberger A, Sobrido MJ, García-Murias M, Domingo A, Sears RL, Lemos RR, Ordoñez-Ugalde A, Nicolas G, da Cunha JE, Rushing EJ, Hugelshofer M, Wurnig MC, Kaech A, Reimann R, Lohmann K, Dobričić V, Carracedo A, Petrović I, Miyasaki JM, Abakumova I, Mäe MA, Raschperger E, Zatz M, Zschiedrich K, Klepper J, Spiteri E, Prieto JM, Navas I, Preuss M, Dering C, Janković M, Paucar M, Svenningsson P, Saliminejad K, Khorshid HR, Novaković I, Aguzzi A, Boss A, Le Ber I, Defer G, Hannequin D, Kostić VS, Campion D, Geschwind DH, Coppola G, Betsholtz C, Klein C, Oliveira JR. Keller A, et al. Nat Genet. 2013 Sep;45(9):1077-82. doi: 10.1038/ng.2723. Epub 2013 Aug 4. Nat Genet. 2013. PMID: 23913003
Notch3 is necessary for blood vessel integrity in the central nervous system.
Henshall TL, Keller A, He L, Johansson BR, Wallgard E, Raschperger E, Mäe MA, Jin S, Betsholtz C, Lendahl U. Henshall TL, et al. Among authors: keller a. Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):409-20. doi: 10.1161/ATVBAHA.114.304849. Epub 2014 Dec 4. Arterioscler Thromb Vasc Biol. 2015. PMID: 25477343 Free article.
Analysis of the brain mural cell transcriptome.
He L, Vanlandewijck M, Raschperger E, Andaloussi Mäe M, Jung B, Lebouvier T, Ando K, Hofmann J, Keller A, Betsholtz C. He L, et al. Among authors: keller a. Sci Rep. 2016 Oct 11;6:35108. doi: 10.1038/srep35108. Sci Rep. 2016. PMID: 27725773 Free PMC article.
Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination.
De La Fuente AG, Lange S, Silva ME, Gonzalez GA, Tempfer H, van Wijngaarden P, Zhao C, Di Canio L, Trost A, Bieler L, Zaunmair P, Rotheneichner P, O'Sullivan A, Couillard-Despres S, Errea O, Mäe MA, Andrae J, He L, Keller A, Bátiz LF, Betsholtz C, Aigner L, Franklin RJM, Rivera FJ. De La Fuente AG, et al. Among authors: keller a. Cell Rep. 2017 Aug 22;20(8):1755-1764. doi: 10.1016/j.celrep.2017.08.007. Cell Rep. 2017. PMID: 28834740 Free PMC article.
A molecular atlas of cell types and zonation in the brain vasculature.
Vanlandewijck M, He L, Mäe MA, Andrae J, Ando K, Del Gaudio F, Nahar K, Lebouvier T, Laviña B, Gouveia L, Sun Y, Raschperger E, Räsänen M, Zarb Y, Mochizuki N, Keller A, Lendahl U, Betsholtz C. Vanlandewijck M, et al. Among authors: keller a. Nature. 2018 Feb 22;554(7693):475-480. doi: 10.1038/nature25739. Epub 2018 Feb 14. Nature. 2018. PMID: 29443965
Author Correction: A molecular atlas of cell types and zonation in the brain vasculature.
Vanlandewijck M, He L, Mäe MA, Andrae J, Ando K, Del Gaudio F, Nahar K, Lebouvier T, Laviña B, Gouveia L, Sun Y, Raschperger E, Räsänen M, Zarb Y, Mochizuki N, Keller A, Lendahl U, Betsholtz C. Vanlandewijck M, et al. Among authors: keller a. Nature. 2018 Aug;560(7716):E3. doi: 10.1038/s41586-018-0232-x. Nature. 2018. PMID: 29925939
2,520 results