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The PNPLA3 rs738409 C > G polymorphism is associated with the risk of progression to cirrhosis in NAFLD patients.
Vespasiani-Gentilucci U, Gallo P, Porcari A, Carotti S, Galati G, Piccioni L, De Vincentis A, Dell'Unto C, Vorini F, Morini S, Riva E, Picardi A. Vespasiani-Gentilucci U, et al. Among authors: morini s. Scand J Gastroenterol. 2016 Aug;51(8):967-73. doi: 10.3109/00365521.2016.1161066. Epub 2016 May 6. Scand J Gastroenterol. 2016. PMID: 27150500
Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology.
Vespasiani-Gentilucci U, Gallo P, Piemonte F, Riva E, Porcari A, Vorini F, Tozzi G, Piccioni L, Galati G, De Vincentis A, Carotti S, Morini S, D'Amico J, Angeletti S, Pedone C, Picardi A. Vespasiani-Gentilucci U, et al. Among authors: morini s. PLoS One. 2016 May 24;11(5):e0156113. doi: 10.1371/journal.pone.0156113. eCollection 2016. PLoS One. 2016. PMID: 27219619 Free PMC article.
Combining Genetic Variants to Improve Risk Prediction for NAFLD and Its Progression to Cirrhosis: A Proof of Concept Study.
Vespasiani-Gentilucci U, Dell'Unto C, De Vincentis A, Baiocchini A, Delle Monache M, Cecere R, Pellicelli AM, Giannelli V, Carotti S, Galati G, Gallo P, Valentini F, Del Nonno F, Rosati D, Morini S, Antonelli-Incalzi R, Picardi A. Vespasiani-Gentilucci U, et al. Among authors: morini s. Can J Gastroenterol Hepatol. 2018 Mar 14;2018:7564835. doi: 10.1155/2018/7564835. eCollection 2018. Can J Gastroenterol Hepatol. 2018. PMID: 29732362 Free PMC article.
Lipophagy Impairment Is Associated With Disease Progression in NAFLD.
Carotti S, Aquilano K, Zalfa F, Ruggiero S, Valentini F, Zingariello M, Francesconi M, Perrone G, Alletto F, Antonelli-Incalzi R, Picardi A, Morini S, Lettieri-Barbato D, Vespasiani-Gentilucci U. Carotti S, et al. Among authors: morini s. Front Physiol. 2020 Jul 17;11:850. doi: 10.3389/fphys.2020.00850. eCollection 2020. Front Physiol. 2020. PMID: 32765301 Free PMC article.
An overview of deregulated lipid metabolism in nonalcoholic fatty liver disease with special focus on lysosomal acid lipase.
Carotti S, Aquilano K, Valentini F, Ruggiero S, Alletto F, Morini S, Picardi A, Antonelli-Incalzi R, Lettieri-Barbato D, Vespasiani-Gentilucci U. Carotti S, et al. Among authors: morini s. Am J Physiol Gastrointest Liver Physiol. 2020 Oct 1;319(4):G469-G480. doi: 10.1152/ajpgi.00049.2020. Epub 2020 Aug 19. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 32812776 Free article. Review.
The Propensity of the Human Liver to Form Large Lipid Droplets Is Associated with PNPLA3 Polymorphism, Reduced INSIG1 and NPC1L1 Expression and Increased Fibrogenetic Capacity.
Ferri F, Carotti S, Carpino G, Mischitelli M, Cantafora A, Molinaro A, Argenziano ME, Parisse S, Corsi A, Riminucci M, Lai Q, Mennini G, Spadetta G, Pugliese F, Rossi M, Morini S, Gaudio E, Ginanni Corradini S. Ferri F, et al. Among authors: morini s. Int J Mol Sci. 2021 Jun 5;22(11):6100. doi: 10.3390/ijms22116100. Int J Mol Sci. 2021. PMID: 34198853 Free PMC article.
Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver.
Carotti S, Lettieri-Barbato D, Piemonte F, Ruggiero S, Rosina M, Zalfa F, Zingariello M, Arciprete F, Valentini F, Francesconi M, D'Amico J, De Vincentis A, Baiocchini A, Perrone G, Antonelli-Incalzi R, Morini S, Picardi A, Aquilano K, Vespasiani-Gentilucci U. Carotti S, et al. Among authors: morini s. Cell Death Dis. 2021 Nov 18;12(12):1092. doi: 10.1038/s41419-021-04382-4. Cell Death Dis. 2021. PMID: 34795230 Free PMC article.
308 results