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Page 1
Age-Related Accumulation of Somatic Mitochondrial DNA Mutations in Adult-Derived Human iPSCs.
Kang E, Wang X, Tippner-Hedges R, Ma H, Folmes CD, Gutierrez NM, Lee Y, Van Dyken C, Ahmed R, Li Y, Koski A, Hayama T, Luo S, Harding CO, Amato P, Jensen J, Battaglia D, Lee D, Wu D, Terzic A, Wolf DP, Huang T, Mitalipov S. Kang E, et al. Among authors: gutierrez nm. Cell Stem Cell. 2016 May 5;18(5):625-36. doi: 10.1016/j.stem.2016.02.005. Epub 2016 Apr 14. Cell Stem Cell. 2016. PMID: 27151456 Free article.
Towards germline gene therapy of inherited mitochondrial diseases.
Tachibana M, Amato P, Sparman M, Woodward J, Sanchis DM, Ma H, Gutierrez NM, Tippner-Hedges R, Kang E, Lee HS, Ramsey C, Masterson K, Battaglia D, Lee D, Wu D, Jensen J, Patton P, Gokhale S, Stouffer R, Mitalipov S. Tachibana M, et al. Among authors: gutierrez nm. Nature. 2013 Jan 31;493(7434):627-31. doi: 10.1038/nature11647. Epub 2012 Oct 24. Nature. 2013. PMID: 23103867 Free PMC article.
Human embryonic stem cells derived by somatic cell nuclear transfer.
Tachibana M, Amato P, Sparman M, Gutierrez NM, Tippner-Hedges R, Ma H, Kang E, Fulati A, Lee HS, Sritanaudomchai H, Masterson K, Larson J, Eaton D, Sadler-Fredd K, Battaglia D, Lee D, Wu D, Jensen J, Patton P, Gokhale S, Stouffer RL, Wolf D, Mitalipov S. Tachibana M, et al. Among authors: gutierrez nm. Cell. 2013 Jun 6;153(6):1228-38. doi: 10.1016/j.cell.2013.05.006. Epub 2013 May 15. Cell. 2013. PMID: 23683578 Free PMC article.
Abnormalities in human pluripotent cells due to reprogramming mechanisms.
Ma H, Morey R, O'Neil RC, He Y, Daughtry B, Schultz MD, Hariharan M, Nery JR, Castanon R, Sabatini K, Thiagarajan RD, Tachibana M, Kang E, Tippner-Hedges R, Ahmed R, Gutierrez NM, Van Dyken C, Polat A, Sugawara A, Sparman M, Gokhale S, Amato P, Wolf DP, Ecker JR, Laurent LC, Mitalipov S. Ma H, et al. Among authors: gutierrez nm. Nature. 2014 Jul 10;511(7508):177-83. doi: 10.1038/nature13551. Epub 2014 Jul 2. Nature. 2014. PMID: 25008523 Free PMC article.
Metabolic rescue in pluripotent cells from patients with mtDNA disease.
Ma H, Folmes CD, Wu J, Morey R, Mora-Castilla S, Ocampo A, Ma L, Poulton J, Wang X, Ahmed R, Kang E, Lee Y, Hayama T, Li Y, Van Dyken C, Gutierrez NM, Tippner-Hedges R, Koski A, Mitalipov N, Amato P, Wolf DP, Huang T, Terzic A, Laurent LC, Izpisua Belmonte JC, Mitalipov S. Ma H, et al. Among authors: gutierrez nm. Nature. 2015 Aug 13;524(7564):234-8. doi: 10.1038/nature14546. Epub 2015 Jul 15. Nature. 2015. PMID: 26176921
Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.
Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, Li Y, Ji D, Kayali R, Cinnioglu C, Olson S, Jensen J, Battaglia D, Lee D, Wu D, Huang T, Wolf DP, Temiakov D, Belmonte JC, Amato P, Mitalipov S. Kang E, et al. Among authors: gutierrez nm. Nature. 2016 Dec 8;540(7632):270-275. doi: 10.1038/nature20592. Epub 2016 Nov 30. Nature. 2016. PMID: 27919073
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs.
Zhao MT, Chen H, Liu Q, Shao NY, Sayed N, Wo HT, Zhang JZ, Ong SG, Liu C, Kim Y, Yang H, Chour T, Ma H, Gutierrez NM, Karakikes I, Mitalipov S, Snyder MP, Wu JC. Zhao MT, et al. Among authors: gutierrez nm. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11111-E11120. doi: 10.1073/pnas.1708991114. Epub 2017 Dec 4. Proc Natl Acad Sci U S A. 2017. PMID: 29203658 Free PMC article.
Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.
Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, Li Y, Ji D, Kayali R, Cinnioglu C, Olson S, Jensen J, Battaglia D, Lee D, Wu D, Huang T, Wolf DP, Temiakov D, Belmonte JCI, Amato P, Mitalipov S. Kang E, et al. Among authors: gutierrez nm. Nature. 2019 Mar;567(7747):E5-E9. doi: 10.1038/s41586-019-0876-1. Nature. 2019. PMID: 30814738
Deleterious mtDNA mutations are common in mature oocytes.
Ma H, Hayama T, Van Dyken C, Darby H, Koski A, Lee Y, Gutierrez NM, Yamada S, Li Y, Andrews M, Ahmed R, Liang D, Gonmanee T, Kang E, Nasser M, Kempton B, Brigande J, McGill TJ, Terzic A, Amato P, Mitalipov S. Ma H, et al. Among authors: gutierrez nm. Biol Reprod. 2020 Mar 13;102(3):607-619. doi: 10.1093/biolre/ioz202. Biol Reprod. 2020. PMID: 31621839 Free PMC article.
Induction of somatic cell haploidy by premature cell division.
Mikhalchenko A, Gutierrez NM, Frana D, Safaei Z, Van Dyken C, Li Y, Ma H, Koski A, Liang D, Lee SG, Amato P, Mitalipov S. Mikhalchenko A, et al. Among authors: gutierrez nm. Sci Adv. 2024 Mar 8;10(10):eadk9001. doi: 10.1126/sciadv.adk9001. Epub 2024 Mar 8. Sci Adv. 2024. PMID: 38457500 Free PMC article.
29 results