Fouché M - Search Results

1

Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure.

Fouché M, Schäfer M, Berghausen J, Desrayaud S, Blatter M, Piéchon P, Dix I, Martin Garcia A, Roth HJ. Fouché M, et al. ChemMedChem. 2016 May 19;11(10):1048-59. doi: 10.1002/cmdc.201600082. Epub 2016 May 6. ChemMedChem. 2016. PMID: 27154275

2

Hydroxymethyl Salicylaldehyde Auxiliary for a Glycine-Dependent Amide-Forming Ligation.

Fouché M, Masse F, Roth HJ. Fouché M, et al. Org Lett. 2015 Oct 16;17(20):4936-9. doi: 10.1021/acs.orglett.5b02350. Epub 2015 Oct 1. Org Lett. 2015. PMID: 26425998

3

Pharmacokinetic Studies around the Mono- and Difunctionalization of a Bioavailable Cyclic Decapeptide Scaffold.

Fouché M, Schäfer M, Blatter M, Berghausen J, Desrayaud S, Roth HJ. Fouché M, et al. ChemMedChem. 2016 May 19;11(10):1060-8. doi: 10.1002/cmdc.201600083. Epub 2016 Apr 20. ChemMedChem. 2016. PMID: 27094987

4

Rationalization of the Membrane Permeability Differences in a Series of Analogue Cyclic Decapeptides.

Witek J, Wang S, Schroeder B, Lingwood R, Dounas A, Roth HJ, Fouché M, Blatter M, Lemke O, Keller B, Riniker S. Witek J, et al. Among authors: fouche m. J Chem Inf Model. 2019 Jan 28;59(1):294-308. doi: 10.1021/acs.jcim.8b00485. Epub 2018 Dec 4. J Chem Inf Model. 2019. PMID: 30457855

5

Effect of Flexibility, Lipophilicity, and the Location of Polar Residues on the Passive Membrane Permeability of a Series of Cyclic Decapeptides.

Wang S, König G, Roth HJ, Fouché M, Rodde S, Riniker S. Wang S, et al. Among authors: fouche m. J Med Chem. 2021 Sep 9;64(17):12761-12773. doi: 10.1021/acs.jmedchem.1c00775. Epub 2021 Aug 18. J Med Chem. 2021. PMID: 34406766 Free article.

6

Polar/apolar interfaces modulate the conformational behavior of cyclic peptides with impact on their passive membrane permeability.

Linker SM, Schellhaas C, Ries B, Roth HJ, Fouché M, Rodde S, Riniker S. Linker SM, et al. Among authors: fouche m. RSC Adv. 2022 Feb 16;12(10):5782-5796. doi: 10.1039/d1ra09025a. eCollection 2022 Feb 16. RSC Adv. 2022. PMID: 35424539 Free PMC article.

7

Lessons for Oral Bioavailability: How Conformationally Flexible Cyclic Peptides Enter and Cross Lipid Membranes.

Linker SM, Schellhaas C, Kamenik AS, Veldhuizen MM, Waibl F, Roth HJ, Fouché M, Rodde S, Riniker S. Linker SM, et al. Among authors: fouche m. J Med Chem. 2023 Feb 23;66(4):2773-2788. doi: 10.1021/acs.jmedchem.2c01837. Epub 2023 Feb 10. J Med Chem. 2023. PMID: 36762908 Free PMC article.

8

Biomimetic total synthesis of cruentaren A via aromatization of diketodioxinones.

Fouché M, Rooney L, Barrett AG. Fouché M, et al. J Org Chem. 2012 Apr 6;77(7):3060-70. doi: 10.1021/jo300225z. Epub 2012 Mar 15. J Org Chem. 2012. PMID: 22401367

9

A model-informed method to retrieve intrinsic from apparent cooperativity and project cellular target occupancy for ternary complex-forming compounds.

Stein RR, Fouché M, Kearns JD, Roth HJ. Stein RR, et al. Among authors: fouche m. RSC Chem Biol. 2023 May 19;4(7):512-523. doi: 10.1039/d2cb00216g. eCollection 2023 Jul 5. RSC Chem Biol. 2023. PMID: 37415863 Free PMC article.

10

Transport capacity is uncoupled with endodormancy breaking in sweet cherry buds: physiological and molecular insights.

Fouché M, Bonnet H, Bonnet DMV, Wenden B. Fouché M, et al. Front Plant Sci. 2023 Nov 14;14:1240642. doi: 10.3389/fpls.2023.1240642. eCollection 2023. Front Plant Sci. 2023. PMID: 38752012 Free PMC article.

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