Ostano P - Search Results

1

Negative control of CSL gene transcription by stress/DNA damage response and p53.

Menietti E, Xu X, Ostano P, Joseph JM, Lefort K, Dotto GP. Menietti E, et al. Among authors: ostano p. Cell Cycle. 2016 Jul 2;15(13):1767-78. doi: 10.1080/15384101.2016.1186317. Epub 2016 May 10. Cell Cycle. 2016. PMID: 27163456 Free PMC article.

2

Negative control of keratinocyte differentiation by Rho/CRIK signaling coupled with up-regulation of KyoT1/2 (FHL1) expression.

Grossi M, Hiou-Feige A, Tommasi Di Vignano A, Calautti E, Ostano P, Lee S, Chiorino G, Dotto GP. Grossi M, et al. Among authors: ostano p. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11313-8. doi: 10.1073/pnas.0505011102. Epub 2005 Aug 1. Proc Natl Acad Sci U S A. 2005. PMID: 16061799 Free PMC article.

3

Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases.

Lefort K, Mandinova A, Ostano P, Kolev V, Calpini V, Kolfschoten I, Devgan V, Lieb J, Raffoul W, Hohl D, Neel V, Garlick J, Chiorino G, Dotto GP. Lefort K, et al. Among authors: ostano p. Genes Dev. 2007 Mar 1;21(5):562-77. doi: 10.1101/gad.1484707. Genes Dev. 2007. PMID: 17344417 Free PMC article.

4

The FoxO3a gene is a key negative target of canonical Notch signalling in the keratinocyte UVB response.

Mandinova A, Lefort K, Tommasi di Vignano A, Stonely W, Ostano P, Chiorino G, Iwaki H, Nakanishi J, Dotto GP. Mandinova A, et al. Among authors: ostano p. EMBO J. 2008 Apr 23;27(8):1243-54. doi: 10.1038/emboj.2008.45. Epub 2008 Apr 3. EMBO J. 2008. PMID: 18388864 Free PMC article.

5

A positive FGFR3/FOXN1 feedback loop underlies benign skin keratosis versus squamous cell carcinoma formation in humans.

Mandinova A, Kolev V, Neel V, Hu B, Stonely W, Lieb J, Wu X, Colli C, Han R, Pazin MJ, Ostano P, Dummer R, Brissette JL, Dotto GP. Mandinova A, et al. Among authors: ostano p. J Clin Invest. 2009 Oct;119(10):3127-37. doi: 10.1172/JCI38543. J Clin Invest. 2009. PMID: 19729838 Free PMC article.

6

Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling.

Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP. Hu B, et al. Among authors: ostano p. Cell. 2012 Jun 8;149(6):1207-20. doi: 10.1016/j.cell.2012.03.048. Cell. 2012. PMID: 22682244 Free PMC article.

7

A miR-34a-SIRT6 axis in the squamous cell differentiation network.

Lefort K, Brooks Y, Ostano P, Cario-André M, Calpini V, Guinea-Viniegra J, Albinger-Hegyi A, Hoetzenecker W, Kolfschoten I, Wagner EF, Werner S, Dotto GP. Lefort K, et al. Among authors: ostano p. EMBO J. 2013 Aug 14;32(16):2248-63. doi: 10.1038/emboj.2013.156. Epub 2013 Jul 16. EMBO J. 2013. PMID: 23860128 Free PMC article.

8

Multifactorial ERβ and NOTCH1 control of squamous differentiation and cancer.

Brooks YS, Ostano P, Jo SH, Dai J, Getsios S, Dziunycz P, Hofbauer GF, Cerveny K, Chiorino G, Lefort K, Dotto GP. Brooks YS, et al. Among authors: ostano p. J Clin Invest. 2014 May;124(5):2260-76. doi: 10.1172/JCI72718. Epub 2014 Apr 17. J Clin Invest. 2014. PMID: 24743148 Free PMC article.

9

A novel Nrf2-miR-29-desmocollin-2 axis regulates desmosome function in keratinocytes.

Kurinna S, Schäfer M, Ostano P, Karouzakis E, Chiorino G, Bloch W, Bachmann A, Gay S, Garrod D, Lefort K, Dotto GP, Beer HD, Werner S. Kurinna S, et al. Among authors: ostano p. Nat Commun. 2014 Oct 6;5:5099. doi: 10.1038/ncomms6099. Nat Commun. 2014. PMID: 25283360 Free article.

10

Combined CSL and p53 downregulation promotes cancer-associated fibroblast activation.

Procopio MG, Laszlo C, Al Labban D, Kim DE, Bordignon P, Jo SH, Goruppi S, Menietti E, Ostano P, Ala U, Provero P, Hoetzenecker W, Neel V, Kilarski WW, Swartz MA, Brisken C, Lefort K, Dotto GP. Procopio MG, et al. Among authors: ostano p. Nat Cell Biol. 2015 Sep;17(9):1193-204. doi: 10.1038/ncb3228. Epub 2015 Aug 24. Nat Cell Biol. 2015. PMID: 26302407 Free PMC article.

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