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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium; Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Pardiñas AF, et al. Among authors: han j. Nat Genet. 2018 Mar;50(3):381-389. doi: 10.1038/s41588-018-0059-2. Epub 2018 Feb 26. Nat Genet. 2018. PMID: 29483656 Free PMC article.
Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, MacCabe JH, McCarroll SA, Baune BT, Breen G, Byrne EM, Dannlowski U, Eley TC, Hayward C, Martin NG, McIntosh AM, Plomin R, Porteous DJ, Wray NR, Caballero A, Geschwind DH, Huckins LM, Ruderfer DM, Santiago E, Sklar P, Stahl EA, Won H, Agerbo E, Als TD, Andreassen OA, Bækvad-Hansen M, Mortensen PB, Pedersen CB, Børglum AD, Bybjerg-Grauholm J, Djurovic S, Durmishi N, Pedersen MG, Golimbet V, Grove J, Hougaard DM, Mattheisen M, Molden E, Mors O, Nordentoft M, Pejovic-Milovancevic M, Sigurdsson E, Silagadze T, Hansen CS, Stefansson K, Stefansson H, Steinberg S, Tosato S, Werge T; GERAD1 Consortium; CRESTAR Consortium; Collier DA, Rujescu D, Kirov G, Owen MJ, O'Donovan MC, Walters JTR. Pardiñas AF, et al. Among authors: han j. Nat Genet. 2019 Jul;51(7):1193. doi: 10.1038/s41588-019-0450-7. Nat Genet. 2019. PMID: 31160808
De novo mutations identified by exome sequencing implicate rare missense variants in SLC6A1 in schizophrenia.
Rees E, Han J, Morgan J, Carrera N, Escott-Price V, Pocklington AJ, Duffield M, Hall LS, Legge SE, Pardiñas AF, Richards AL, Roth J, Lezheiko T, Kondratyev N, Kaleda V, Golimbet V, Parellada M, González-Peñas J, Arango C; GROUP Investigators; Gawlik M, Kirov G, Walters JTR, Holmans P, O'Donovan MC, Owen MJ. Rees E, et al. Among authors: han j. Nat Neurosci. 2020 Feb;23(2):179-184. doi: 10.1038/s41593-019-0565-2. Epub 2020 Jan 13. Nat Neurosci. 2020. PMID: 31932766 Free PMC article.
Sleep disturbances as risk factors for neurodegeneration later in life.
Simmonds E, Levine KS, Han J, Iwaki H, Koretsky MJ, Kuznetsov N, Faghri F, Solsberg CW, Schuh A, Jones L, Bandres-Ciga S, Blauwendraat C, Singleton A, Escott-Price V, Leonard HL, Nalls MA. Simmonds E, et al. Among authors: han j. medRxiv [Preprint]. 2023 Nov 9:2023.11.08.23298037. doi: 10.1101/2023.11.08.23298037. medRxiv. 2023. PMID: 37986827 Free PMC article. Preprint.
Severe psychiatric disorders are associated with increased risk of dementia.
Stevenson-Hoare J, Legge SE, Simmonds E, Han J, Owen MJ, O'Donovan M, Kirov G, Escott-Price V. Stevenson-Hoare J, et al. Among authors: han j. BMJ Ment Health. 2024 Jun 17;27(1):e301097. doi: 10.1136/bmjment-2024-301097. BMJ Ment Health. 2024. PMID: 38886095 Free PMC article.
A Cross-Linked Coating Loaded with Antimicrobial Peptides for Corrosion Control, Early Antibacterial, and Sequential Osteogenic Promotion on a Magnesium Alloy as Orthopedic Implants.
Zhang H, Zhang P, Shen X, Han J, Wang H, Qin H, Wang B, Qian J, Udduttula A, Luo R, Zhao K, Wang Y, Chen Y. Zhang H, et al. Among authors: han j. Acta Biomater. 2024 Dec 21:S1742-7061(24)00765-7. doi: 10.1016/j.actbio.2024.12.046. Online ahead of print. Acta Biomater. 2024. PMID: 39716540
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