Price JL - Search Results

1

Conjugation Strategy Strongly Impacts the Conformational Stability of a PEG-Protein Conjugate.

Lawrence PB, Billings WM, Miller MB, Pandey BK, Stephens AR, Langlois MI, Price JL. Lawrence PB, et al. Among authors: price jl. ACS Chem Biol. 2016 Jul 15;11(7):1805-9. doi: 10.1021/acschembio.6b00349. Epub 2016 May 20. ACS Chem Biol. 2016. PMID: 27191252 Free PMC article.

2

Impact of site-specific PEGylation on the conformational stability and folding rate of the Pin WW domain depends strongly on PEG oligomer length.

Pandey BK, Smith MS, Torgerson C, Lawrence PB, Matthews SS, Watkins E, Groves ML, Prigozhin MB, Price JL. Pandey BK, et al. Among authors: price jl. Bioconjug Chem. 2013 May 15;24(5):796-802. doi: 10.1021/bc3006122. Epub 2013 Apr 26. Bioconjug Chem. 2013. PMID: 23578107

3

Stabilizing impact of N-glycosylation on the WW domain depends strongly on the Asn-GlcNAc linkage.

Pandey BK, Enck S, Price JL. Pandey BK, et al. Among authors: price jl. ACS Chem Biol. 2013 Oct 18;8(10):2140-4. doi: 10.1021/cb4004496. Epub 2013 Aug 20. ACS Chem Biol. 2013. PMID: 23937634

4

Two structural scenarios for protein stabilization by PEG.

Chao SH, Matthews SS, Paxman R, Aksimentiev A, Gruebele M, Price JL. Chao SH, et al. Among authors: price jl. J Phys Chem B. 2014 Jul 17;118(28):8388-95. doi: 10.1021/jp502234s. Epub 2014 Jun 2. J Phys Chem B. 2014. PMID: 24821319

5

Cys(i)-Lys(i+3)-Lys(i+4) triad: a general approach for PEG-based stabilization of α-helical proteins.

Pandey BK, Smith MS, Price JL. Pandey BK, et al. Among authors: price jl. Biomacromolecules. 2014 Dec 8;15(12):4643-7. doi: 10.1021/bm501546k. Epub 2014 Nov 11. Biomacromolecules. 2014. PMID: 25387132

6

Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.

Lawrence PB, Gavrilov Y, Matthews SS, Langlois MI, Shental-Bechor D, Greenblatt HM, Pandey BK, Smith MS, Paxman R, Torgerson CD, Merrell JP, Ritz CC, Prigozhin MB, Levy Y, Price JL. Lawrence PB, et al. Among authors: price jl. J Am Chem Soc. 2014 Dec 17;136(50):17547-60. doi: 10.1021/ja5095183. Epub 2014 Dec 4. J Am Chem Soc. 2014. PMID: 25409346

7

How PEGylation influences protein conformational stability.

Lawrence PB, Price JL. Lawrence PB, et al. Among authors: price jl. Curr Opin Chem Biol. 2016 Oct;34:88-94. doi: 10.1016/j.cbpa.2016.08.006. Epub 2016 Aug 28. Curr Opin Chem Biol. 2016. PMID: 27580482 Free PMC article. Review.

8

Enhancing a long-range salt bridge with intermediate aromatic and nonpolar amino acids.

Smith MS, Billings WM, Whitby FG, Miller MB, Price JL. Smith MS, et al. Among authors: price jl. Org Biomol Chem. 2017 Jul 19;15(28):5882-5886. doi: 10.1039/c7ob01198a. Org Biomol Chem. 2017. PMID: 28678274

9

An Anion-π Interaction Strongly Stabilizes the β-Sheet Protein WW.

Smith MS, Lawrence EEK, Billings WM, Larsen KS, Bécar NA, Price JL. Smith MS, et al. Among authors: price jl. ACS Chem Biol. 2017 Oct 20;12(10):2535-2537. doi: 10.1021/acschembio.7b00768. Epub 2017 Sep 14. ACS Chem Biol. 2017. PMID: 28886246

10

Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location.

Draper SRE, Lawrence PB, Billings WM, Xiao Q, Brown NP, Bécar NA, Matheson DJ, Stephens AR, Price JL. Draper SRE, et al. Among authors: price jl. Bioconjug Chem. 2017 Oct 18;28(10):2507-2513. doi: 10.1021/acs.bioconjchem.7b00281. Epub 2017 Oct 9. Bioconjug Chem. 2017. PMID: 28972368 Free PMC article.

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