Rose-John S - Search Results

1

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth.

Nivarthi H, Gordziel C, Themanns M, Kramer N, Eberl M, Rabe B, Schlederer M, Rose-John S, Knösel T, Kenner L, Freund P, Aberger F, Han X, Kralovics R, Dolznig H, Jennek S, Friedrich K, Moriggl R. Nivarthi H, et al. Oncotarget. 2016 Aug 9;7(32):51096-51106. doi: 10.18632/oncotarget.9315. Oncotarget. 2016. PMID: 27191495 Free PMC article.

2

Development of a monoclonal antibody-based enzyme-linked immunoabsorbent assay for the binding of gp130 to the IL-6/IL-6R complex and its competitive inhibition.

Scheller J, Kovaleva M, Rabe B, Eichler J, Kallen KJ, Rose-John S. Scheller J, et al. J Immunol Methods. 2004 Aug;291(1-2):93-100. doi: 10.1016/j.jim.2004.05.002. J Immunol Methods. 2004. PMID: 15345308

3

Abrogation of viral interleukin-6 (vIL-6)-induced signaling by intracellular retention and neutralization of vIL-6 with an anti-vIL-6 single-chain antibody selected by phage display.

Kovaleva M, Bussmeyer I, Rabe B, Grötzinger J, Sudarman E, Eichler J, Conrad U, Rose-John S, Scheller J. Kovaleva M, et al. J Virol. 2006 Sep;80(17):8510-20. doi: 10.1128/JVI.00420-06. J Virol. 2006. PMID: 16912301 Free PMC article.

4

Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils.

Chalaris A, Rabe B, Paliga K, Lange H, Laskay T, Fielding CA, Jones SA, Rose-John S, Scheller J. Chalaris A, et al. Blood. 2007 Sep 15;110(6):1748-55. doi: 10.1182/blood-2007-01-067918. Epub 2007 Jun 13. Blood. 2007. PMID: 17567983 Free article.

5

Transgenic blockade of interleukin 6 transsignaling abrogates inflammation.

Rabe B, Chalaris A, May U, Waetzig GH, Seegert D, Williams AS, Jones SA, Rose-John S, Scheller J. Rabe B, et al. Blood. 2008 Feb 1;111(3):1021-8. doi: 10.1182/blood-2007-07-102137. Epub 2007 Nov 7. Blood. 2008. PMID: 17989316 Free article.

6

Structure-guided optimization of the interleukin-6 trans-signaling antagonist sgp130.

Tenhumberg S, Waetzig GH, Chalaris A, Rabe B, Seegert D, Scheller J, Rose-John S, Grötzinger J. Tenhumberg S, et al. J Biol Chem. 2008 Oct 3;283(40):27200-7. doi: 10.1074/jbc.M803694200. Epub 2008 Jul 23. J Biol Chem. 2008. PMID: 18650419 Free article.

7

Unraveling viral interleukin-6 binding to gp130 and activation of STAT-signaling pathways independently of the interleukin-6 receptor.

Adam N, Rabe B, Suthaus J, Grötzinger J, Rose-John S, Scheller J. Adam N, et al. J Virol. 2009 May;83(10):5117-26. doi: 10.1128/JVI.01601-08. Epub 2009 Mar 4. J Virol. 2009. PMID: 19264784 Free PMC article.

8

Interleukin-6 trans-signaling regulates glycogen consumption after D-galactosamine-induced liver damage.

Drucker C, Rabe B, Chalaris A, Schulz E, Scheller J, Rose-John S. Drucker C, et al. J Interferon Cytokine Res. 2009 Nov;29(11):711-8. doi: 10.1089/jir.2008.0095. J Interferon Cytokine Res. 2009. PMID: 19642894

9

The soluble Interleukin 6 receptor: generation and role in inflammation and cancer.

Chalaris A, Garbers C, Rabe B, Rose-John S, Scheller J. Chalaris A, et al. Eur J Cell Biol. 2011 Jun-Jul;90(6-7):484-94. doi: 10.1016/j.ejcb.2010.10.007. Epub 2010 Dec 8. Eur J Cell Biol. 2011. PMID: 21145125 Review.

10

IL-6 trans-signaling promotes pancreatitis-associated lung injury and lethality.

Zhang H, Neuhöfer P, Song L, Rabe B, Lesina M, Kurkowski MU, Treiber M, Wartmann T, Regnér S, Thorlacius H, Saur D, Weirich G, Yoshimura A, Halangk W, Mizgerd JP, Schmid RM, Rose-John S, Algül H. Zhang H, et al. J Clin Invest. 2013 Mar;123(3):1019-31. doi: 10.1172/JCI64931. Epub 2013 Feb 15. J Clin Invest. 2013. PMID: 23426178 Free PMC article.

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