Ernst K - Search Results

1

Host Cell Chaperones Hsp70/Hsp90 and Peptidyl-Prolyl Cis/Trans Isomerases Are Required for the Membrane Translocation of Bacterial ADP-Ribosylating Toxins.

Ernst K, Schnell L, Barth H. Ernst K, et al. Curr Top Microbiol Immunol. 2017;406:163-198. doi: 10.1007/82_2016_14. Curr Top Microbiol Immunol. 2017. PMID: 27197646 Review.

2

Membrane translocation of binary actin-ADP-ribosylating toxins from Clostridium difficile and Clostridium perfringens is facilitated by cyclophilin A and Hsp90.

Kaiser E, Kroll C, Ernst K, Schwan C, Popoff M, Fischer G, Buchner J, Aktories K, Barth H. Kaiser E, et al. Among authors: ernst k. Infect Immun. 2011 Oct;79(10):3913-21. doi: 10.1128/IAI.05372-11. Epub 2011 Jul 18. Infect Immun. 2011. PMID: 21768281 Free PMC article.

3

FK506-binding protein 51 interacts with Clostridium botulinum C2 toxin and FK506 inhibits membrane translocation of the toxin in mammalian cells.

Kaiser E, Böhm N, Ernst K, Langer S, Schwan C, Aktories K, Popoff M, Fischer G, Barth H. Kaiser E, et al. Among authors: ernst k. Cell Microbiol. 2012 Aug;14(8):1193-205. doi: 10.1111/j.1462-5822.2012.01788.x. Epub 2012 Apr 12. Cell Microbiol. 2012. PMID: 22420783

4

The chaperone Hsp90 and PPIases of the cyclophilin and FKBP families facilitate membrane translocation of Photorhabdus luminescens ADP-ribosyltransferases.

Lang AE, Ernst K, Lee H, Papatheodorou P, Schwan C, Barth H, Aktories K. Lang AE, et al. Among authors: ernst k. Cell Microbiol. 2014 Apr;16(4):490-503. doi: 10.1111/cmi.12228. Epub 2013 Nov 5. Cell Microbiol. 2014. PMID: 24138221

5

Cyclophilin-facilitated membrane translocation as pharmacological target to prevent intoxication of mammalian cells by binary clostridial actin ADP-ribosylated toxins.

Ernst K, Langer S, Kaiser E, Osseforth C, Michaelis J, Popoff MR, Schwan C, Aktories K, Kahlert V, Malesevic M, Schiene-Fischer C, Barth H. Ernst K, et al. J Mol Biol. 2015 Mar 27;427(6 Pt A):1224-38. doi: 10.1016/j.jmb.2014.07.013. Epub 2014 Jul 21. J Mol Biol. 2015. PMID: 25058685 Free article.

6

A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin.

Ernst K, Liebscher M, Mathea S, Granzhan A, Schmid J, Popoff MR, Ihmels H, Barth H, Schiene-Fischer C. Ernst K, et al. Sci Rep. 2016 Feb 3;6:20301. doi: 10.1038/srep20301. Sci Rep. 2016. PMID: 26839186 Free PMC article.

7

Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells.

Ernst K, Schmid J, Beck M, Hägele M, Hohwieler M, Hauff P, Ückert AK, Anastasia A, Fauler M, Jank T, Aktories K, Popoff MR, Schiene-Fischer C, Kleger A, Müller M, Frick M, Barth H. Ernst K, et al. Sci Rep. 2017 Jun 2;7(1):2724. doi: 10.1038/s41598-017-02882-y. Sci Rep. 2017. PMID: 28578412 Free PMC article.

8

Pharmacological Cyclophilin Inhibitors Prevent Intoxication of Mammalian Cells with Bordetella pertussis Toxin.

Ernst K, Eberhardt N, Mittler AK, Sonnabend M, Anastasia A, Freisinger S, Schiene-Fischer C, Malešević M, Barth H. Ernst K, et al. Toxins (Basel). 2018 May 1;10(5):181. doi: 10.3390/toxins10050181. Toxins (Basel). 2018. PMID: 29723951 Free PMC article.

9

Combined Pharmacological Inhibition of Cyclophilins, FK506-Binding Proteins, Hsp90, and Hsp70 Protects Cells From Clostridium botulinum C2 Toxin.

Ernst K, Kling C, Landenberger M, Barth H. Ernst K, et al. Front Pharmacol. 2018 Nov 13;9:1287. doi: 10.3389/fphar.2018.01287. eCollection 2018. Front Pharmacol. 2018. PMID: 30483129 Free PMC article.

10

Intoxication of mammalian cells with binary clostridial enterotoxins is inhibited by the combination of pharmacological chaperone inhibitors.

Ernst K, Sailer J, Braune M, Barth H. Ernst K, et al. Naunyn Schmiedebergs Arch Pharmacol. 2021 May;394(5):941-954. doi: 10.1007/s00210-020-02029-3. Epub 2020 Dec 7. Naunyn Schmiedebergs Arch Pharmacol. 2021. PMID: 33284399 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

502 results

Search Page

Filters