Lee EF - Search Results

1

Physiological restraint of Bak by Bcl-xL is essential for cell survival.

Lee EF, Grabow S, Chappaz S, Dewson G, Hockings C, Kluck RM, Debrincat MA, Gray DH, Witkowski MT, Evangelista M, Pettikiriarachchi A, Bouillet P, Lane RM, Czabotar PE, Colman PM, Smith BJ, Kile BT, Fairlie WD. Lee EF, et al. Genes Dev. 2016 May 15;30(10):1240-50. doi: 10.1101/gad.279414.116. Epub 2016 May 19. Genes Dev. 2016. PMID: 27198225 Free PMC article.

2

Affinity maturation of leukemia inhibitory factor and conversion to potent antagonists of signaling.

Fairlie WD, Uboldi AD, McCoubrie JE, Wang CC, Lee EF, Yao S, De Souza DP, Mifsud S, Metcalf D, Nicola NA, Norton RS, Baca M. Fairlie WD, et al. Among authors: lee ef. J Biol Chem. 2004 Jan 16;279(3):2125-34. doi: 10.1074/jbc.M310103200. Epub 2003 Oct 29. J Biol Chem. 2004. PMID: 14585833 Free article.

3

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.

Willis SN, Fletcher JI, Kaufmann T, van Delft MF, Chen L, Czabotar PE, Ierino H, Lee EF, Fairlie WD, Bouillet P, Strasser A, Kluck RM, Adams JM, Huang DC. Willis SN, et al. Among authors: lee ef. Science. 2007 Feb 9;315(5813):856-9. doi: 10.1126/science.1133289. Science. 2007. PMID: 17289999

4

A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and Bak.

Kvansakul M, van Delft MF, Lee EF, Gulbis JM, Fairlie WD, Huang DC, Colman PM. Kvansakul M, et al. Among authors: lee ef. Mol Cell. 2007 Mar 23;25(6):933-42. doi: 10.1016/j.molcel.2007.02.004. Mol Cell. 2007. PMID: 17386268 Free article.

5

Structural insights into the degradation of Mcl-1 induced by BH3 domains.

Czabotar PE, Lee EF, van Delft MF, Day CL, Smith BJ, Huang DC, Fairlie WD, Hinds MG, Colman PM. Czabotar PE, et al. Among authors: lee ef. Proc Natl Acad Sci U S A. 2007 Apr 10;104(15):6217-22. doi: 10.1073/pnas.0701297104. Epub 2007 Mar 27. Proc Natl Acad Sci U S A. 2007. PMID: 17389404 Free PMC article.

6

Crystal structure of ABT-737 complexed with Bcl-xL: implications for selectivity of antagonists of the Bcl-2 family.

Lee EF, Czabotar PE, Smith BJ, Deshayes K, Zobel K, Colman PM, Fairlie WD. Lee EF, et al. Cell Death Differ. 2007 Sep;14(9):1711-3. doi: 10.1038/sj.cdd.4402178. Epub 2007 Jun 15. Cell Death Differ. 2007. PMID: 17572662 No abstract available.

7

A novel BH3 ligand that selectively targets Mcl-1 reveals that apoptosis can proceed without Mcl-1 degradation.

Lee EF, Czabotar PE, van Delft MF, Michalak EM, Boyle MJ, Willis SN, Puthalakath H, Bouillet P, Colman PM, Huang DC, Fairlie WD. Lee EF, et al. J Cell Biol. 2008 Jan 28;180(2):341-55. doi: 10.1083/jcb.200708096. Epub 2008 Jan 21. J Cell Biol. 2008. PMID: 18209102 Free PMC article.

8

EGL-1 BH3 mutants reveal the importance of protein levels and target affinity for cell-killing potency.

Lee EF, Chen L, Yang H, Colman PM, Huang DC, Fairlie WD. Lee EF, et al. Cell Death Differ. 2008 Oct;15(10):1609-18. doi: 10.1038/cdd.2008.86. Epub 2008 Jun 20. Cell Death Differ. 2008. PMID: 18566606

9

Structure of the BH3 domains from the p53-inducible BH3-only proteins Noxa and Puma in complex with Mcl-1.

Day CL, Smits C, Fan FC, Lee EF, Fairlie WD, Hinds MG. Day CL, et al. Among authors: lee ef. J Mol Biol. 2008 Jul 25;380(5):958-71. doi: 10.1016/j.jmb.2008.05.071. Epub 2008 Jun 4. J Mol Biol. 2008. PMID: 18589438

10

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.

Fletcher JI, Meusburger S, Hawkins CJ, Riglar DT, Lee EF, Fairlie WD, Huang DC, Adams JM. Fletcher JI, et al. Among authors: lee ef. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18081-7. doi: 10.1073/pnas.0808691105. Epub 2008 Nov 3. Proc Natl Acad Sci U S A. 2008. PMID: 18981409 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

111 results

Search Page

Filters