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Inhibition of IRF5 hyperactivation protects from lupus onset and severity.
Song S, De S, Nelson V, Chopra S, LaPan M, Kampta K, Sun S, He M, Thompson CD, Li D, Shih T, Tan N, Al-Abed Y, Capitle E, Aranow C, Mackay M, Clapp WL, Barnes BJ. Song S, et al. Among authors: sun s. J Clin Invest. 2020 Dec 1;130(12):6700-6717. doi: 10.1172/JCI120288. J Clin Invest. 2020. PMID: 32897883 Free PMC article. Clinical Trial.
Amending HIV Drugs: A Novel Small-Molecule Approach To Target Lupus Anti-DNA Antibodies.
VanPatten S, Sun S, He M, Cheng KF, Altiti A, Papatheodorou A, Kowal C, Jeganathan V, Crawford JM, Bloom O, Volpe BT, Grant C, Meurice N, Coleman TR, Diamond B, Al-Abed Y. VanPatten S, et al. Among authors: sun s. J Med Chem. 2016 Oct 13;59(19):8859-8867. doi: 10.1021/acs.jmedchem.6b00694. Epub 2016 Sep 20. J Med Chem. 2016. PMID: 27603688 Free PMC article.
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