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Page 1
High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement.
De Tavernier E, Detalle L, Morizzo E, Roobrouck A, De Taeye S, Rieger M, Verhaeghe T, Correia A, Van Hegelsom R, Figueirido R, Noens J, Steffensen S, Stöhr T, Van de Velde W, Depla E, Dombrecht B. De Tavernier E, et al. Among authors: roobrouck a. J Biol Chem. 2016 Jul 15;291(29):15243-55. doi: 10.1074/jbc.M115.684241. Epub 2016 May 20. J Biol Chem. 2016. PMID: 27226529 Free PMC article.
Potent and efficacious inhibition of CXCR2 signaling by biparatopic nanobodies combining two distinct modes of action.
Bradley ME, Dombrecht B, Manini J, Willis J, Vlerick D, De Taeye S, Van den Heede K, Roobrouck A, Grot E, Kent TC, Laeremans T, Steffensen S, Van Heeke G, Brown Z, Charlton SJ, Cromie KD. Bradley ME, et al. Among authors: roobrouck a. Mol Pharmacol. 2015 Feb;87(2):251-62. doi: 10.1124/mol.114.094821. Epub 2014 Dec 2. Mol Pharmacol. 2015. PMID: 25468882
Prevention of hepatitis B infections: vaccination and its limitations.
Leroux-Roels G, Cao T, De Knibber A, Meuleman P, Roobrouck A, Farhoudi A, Vanlandschoot P, Desombere I. Leroux-Roels G, et al. Among authors: roobrouck a. Acta Clin Belg. 2001 Jul-Aug;56(4):209-19. doi: 10.1179/acb.2001.032. Acta Clin Belg. 2001. PMID: 11603250 Review.
Early infections by myxoma virus of young rabbits (Oryctolagus cuniculus) protected by maternal antibodies activate their immune system and enhance herd immunity in wild populations.
Marchandeau S, Pontier D, Guitton JS, Letty J, Fouchet D, Aubineau J, Berger F, Léonard Y, Roobrouck A, Gelfi J, Peralta B, Bertagnoli S. Marchandeau S, et al. Among authors: roobrouck a. Vet Res. 2014 Mar 4;45(1):26. doi: 10.1186/1297-9716-45-26. Vet Res. 2014. PMID: 24589193 Free PMC article.