McKenna A - Search Results

1

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. McKenna A, et al. Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26. Science. 2016. PMID: 27229144 Free PMC article.

2

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain.

Raj B, Wagner DE, McKenna A, Pandey S, Klein AM, Shendure J, Gagnon JA, Schier AF. Raj B, et al. Among authors: mckenna a. Nat Biotechnol. 2018 Jun;36(5):442-450. doi: 10.1038/nbt.4103. Epub 2018 Mar 28. Nat Biotechnol. 2018. PMID: 29608178 Free PMC article.

3

Recording development with single cell dynamic lineage tracing.

McKenna A, Gagnon JA. McKenna A, et al. Development. 2019 Jun 27;146(12):dev169730. doi: 10.1242/dev.169730. Development. 2019. PMID: 31249005 Free PMC article. Review.

4

CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.

Gasperini M, Findlay GM, McKenna A, Milbank JH, Lee C, Zhang MD, Cusanovich DA, Shendure J. Gasperini M, et al. Among authors: mckenna a. Am J Hum Genet. 2017 Aug 3;101(2):192-205. doi: 10.1016/j.ajhg.2017.06.010. Epub 2017 Jul 14. Am J Hum Genet. 2017. PMID: 28712454 Free PMC article.

5

FlashFry: a fast and flexible tool for large-scale CRISPR target design.

McKenna A, Shendure J. McKenna A, et al. BMC Biol. 2018 Jul 5;16(1):74. doi: 10.1186/s12915-018-0545-0. BMC Biol. 2018. PMID: 29976198 Free PMC article.

6

Emergence of Neuronal Diversity during Vertebrate Brain Development.

Raj B, Farrell JA, Liu J, El Kholtei J, Carte AN, Navajas Acedo J, Du LY, McKenna A, Relić Đ, Leslie JM, Schier AF. Raj B, et al. Among authors: mckenna a. Neuron. 2020 Dec 23;108(6):1058-1074.e6. doi: 10.1016/j.neuron.2020.09.023. Epub 2020 Oct 16. Neuron. 2020. PMID: 33068532 Free PMC article.

7

Single-cell lineage tracing of metastatic cancer reveals selection of hybrid EMT states.

Simeonov KP, Byrns CN, Clark ML, Norgard RJ, Martin B, Stanger BZ, Shendure J, McKenna A, Lengner CJ. Simeonov KP, et al. Among authors: mckenna a. Cancer Cell. 2021 Aug 9;39(8):1150-1162.e9. doi: 10.1016/j.ccell.2021.05.005. Epub 2021 Jun 10. Cancer Cell. 2021. PMID: 34115987 Free PMC article.

8

Simultaneous brain cell type and lineage determined by scRNA-seq reveals stereotyped cortical development.

Anderson DJ, Pauler FM, McKenna A, Shendure J, Hippenmeyer S, Horwitz MS. Anderson DJ, et al. Among authors: mckenna a. Cell Syst. 2022 Jun 15;13(6):438-453.e5. doi: 10.1016/j.cels.2022.03.006. Epub 2022 Apr 21. Cell Syst. 2022. PMID: 35452605 Free PMC article.

9

Diversity of human copy number variation and multicopy genes.

Sudmant PH, Kitzman JO, Antonacci F, Alkan C, Malig M, Tsalenko A, Sampas N, Bruhn L, Shendure J; 1000 Genomes Project; Eichler EE. Sudmant PH, et al. Science. 2010 Oct 29;330(6004):641-6. doi: 10.1126/science.1197005. Science. 2010. PMID: 21030649 Free PMC article.

10

Massively parallel profiling and predictive modeling of the outcomes of CRISPR/Cas9-mediated double-strand break repair.

Chen W, McKenna A, Schreiber J, Haeussler M, Yin Y, Agarwal V, Noble WS, Shendure J. Chen W, et al. Among authors: mckenna a. Nucleic Acids Res. 2019 Sep 5;47(15):7989-8003. doi: 10.1093/nar/gkz487. Nucleic Acids Res. 2019. PMID: 31165867 Free PMC article.

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