Schier AF - Search Results

1

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. McKenna A, et al. Among authors: schier af. Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26. Science. 2016. PMID: 27229144 Free PMC article.

2

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.

Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Merkle FT, et al. Among authors: schier af. Cell Rep. 2015 May 12;11(6):875-883. doi: 10.1016/j.celrep.2015.04.007. Epub 2015 Apr 30. Cell Rep. 2015. PMID: 25937281 Free PMC article.

3

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs.

Gagnon JA, Valen E, Thyme SB, Huang P, Akhmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Gagnon JA, et al. Among authors: schier af. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PLoS One. 2014. PMID: 24873830 Free PMC article.

4

Emergence of Neuronal Diversity during Vertebrate Brain Development.

Raj B, Farrell JA, Liu J, El Kholtei J, Carte AN, Navajas Acedo J, Du LY, McKenna A, Relić Đ, Leslie JM, Schier AF. Raj B, et al. Among authors: schier af. Neuron. 2020 Dec 23;108(6):1058-1074.e6. doi: 10.1016/j.neuron.2020.09.023. Epub 2020 Oct 16. Neuron. 2020. PMID: 33068532 Free PMC article.

5

Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9.

Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Liu J, et al. Among authors: schier af. Development. 2015 Mar 15;142(6):1113-24. doi: 10.1242/dev.117424. Epub 2015 Feb 27. Development. 2015. PMID: 25725064 Free PMC article.

6

Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function.

Ma M, Ramirez AD, Wang T, Roberts RL, Harmon KE, Schoppik D, Sharma A, Kuang C, Goei SL, Gagnon JA, Zimmerman S, Tsai SQ, Reyon D, Joung JK, Aksay ERF, Schier AF, Pan YA. Ma M, et al. Among authors: schier af. J Neurosci. 2020 Jan 2;40(1):143-158. doi: 10.1523/JNEUROSCI.1783-19.2019. Epub 2019 Nov 4. J Neurosci. 2020. PMID: 31685652 Free PMC article.

7

Zebrabow: multispectral cell labeling for cell tracing and lineage analysis in zebrafish.

Pan YA, Freundlich T, Weissman TA, Schoppik D, Wang XC, Zimmerman S, Ciruna B, Sanes JR, Lichtman JW, Schier AF. Pan YA, et al. Among authors: schier af. Development. 2013 Jul;140(13):2835-46. doi: 10.1242/dev.094631. Development. 2013. PMID: 23757414 Free PMC article.

8

Internal guide RNA interactions interfere with Cas9-mediated cleavage.

Thyme SB, Akhmetova L, Montague TG, Valen E, Schier AF. Thyme SB, et al. Among authors: schier af. Nat Commun. 2016 Jun 10;7:11750. doi: 10.1038/ncomms11750. Nat Commun. 2016. PMID: 27282953 Free PMC article.

9

Spatial reconstruction of single-cell gene expression data.

Satija R, Farrell JA, Gennert D, Schier AF, Regev A. Satija R, et al. Among authors: schier af. Nat Biotechnol. 2015 May;33(5):495-502. doi: 10.1038/nbt.3192. Epub 2015 Apr 13. Nat Biotechnol. 2015. PMID: 25867923 Free PMC article.

10

A Massively Parallel Reporter Assay of 3' UTR Sequences Identifies In Vivo Rules for mRNA Degradation.

Rabani M, Pieper L, Chew GL, Schier AF. Rabani M, et al. Among authors: schier af. Mol Cell. 2017 Dec 21;68(6):1083-1094.e5. doi: 10.1016/j.molcel.2017.11.014. Epub 2017 Dec 7. Mol Cell. 2017. PMID: 29225039 Free PMC article.

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