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Origins of the cytolytic synapse.
de la Roche M, Asano Y, Griffiths GM. de la Roche M, et al. Nat Rev Immunol. 2016 Jul;16(7):421-32. doi: 10.1038/nri.2016.54. Epub 2016 Jun 6. Nat Rev Immunol. 2016. PMID: 27265595 Review.
Aging increases cell-to-cell transcriptional variability upon immune stimulation.
Martinez-Jimenez CP, Eling N, Chen HC, Vallejos CA, Kolodziejczyk AA, Connor F, Stojic L, Rayner TF, Stubbington MJT, Teichmann SA, de la Roche M, Marioni JC, Odom DT. Martinez-Jimenez CP, et al. Among authors: de la roche m. Science. 2017 Mar 31;355(6332):1433-1436. doi: 10.1126/science.aah4115. Science. 2017. PMID: 28360329 Free PMC article.
Cell-autonomous Hedgehog signaling controls Th17 polarization and pathogenicity.
Hanna J, Beke F, O'Brien LM, Kapeni C, Chen HC, Carbonaro V, Kim AB, Kishore K, Adolph TE, Skjoedt MO, Skjoedt K, de la Roche M, de la Roche M. Hanna J, et al. Among authors: de la roche m. Nat Commun. 2022 Jul 14;13(1):4075. doi: 10.1038/s41467-022-31722-5. Nat Commun. 2022. PMID: 35835905 Free PMC article.
Primary Cilia Mediate Diverse Kinase Inhibitor Resistance Mechanisms in Cancer.
Jenks AD, Vyse S, Wong JP, Kostaras E, Keller D, Burgoyne T, Shoemark A, Tsalikis A, de la Roche M, Michaelis M, Cinatl J Jr, Huang PH, Tanos BE. Jenks AD, et al. Among authors: de la roche m. Cell Rep. 2018 Jun 5;23(10):3042-3055. doi: 10.1016/j.celrep.2018.05.016. Cell Rep. 2018. PMID: 29874589 Free PMC article.
A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo.
Cassidy LD, Young AR, Pérez-Mancera PA, Nimmervoll B, Jaulim A, Chen HC, McIntyre DJO, Brais R, Ricketts T, Pacey S, De La Roche M, Gilbertson RJ, Rubinsztein DC, Narita M. Cassidy LD, et al. Among authors: de la roche m. Autophagy. 2018;14(7):1256-1266. doi: 10.1080/15548627.2018.1458172. Epub 2018 Jul 12. Autophagy. 2018. PMID: 29999454 Free PMC article.
49 results