Jones PP - Search Results

1

Oxidation of RyR2 Has a Biphasic Effect on the Threshold for Store Overload-Induced Calcium Release.

Waddell HMM, Zhang JZ, Hoeksema KJ, McLachlan JJ, McLay JC, Jones PP. Waddell HMM, et al. Among authors: jones pp. Biophys J. 2016 Jun 7;110(11):2386-2396. doi: 10.1016/j.bpj.2016.04.036. Biophys J. 2016. PMID: 27276257 Free PMC article.

2

The CPVT-associated RyR2 mutation G230C enhances store overload-induced Ca2+ release and destabilizes the N-terminal domains.

Liu Y, Kimlicka L, Hiess F, Tian X, Wang R, Zhang L, Jones PP, Van Petegem F, Chen SR. Liu Y, et al. Among authors: jones pp. Biochem J. 2013 Aug 15;454(1):123-31. doi: 10.1042/BJ20130594. Biochem J. 2013. PMID: 23746327

3

The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+).

Zhang JZ, McLay JC, Jones PP. Zhang JZ, et al. Among authors: jones pp. J Mol Cell Cardiol. 2014 Sep;74:22-31. doi: 10.1016/j.yjmcc.2014.04.019. Epub 2014 May 5. J Mol Cell Cardiol. 2014. PMID: 24805197

4

Regulation of RYR2 by sarcoplasmic reticulum Ca(2+).

Zhang JZ, Waddell HM, Jones PP. Zhang JZ, et al. Among authors: jones pp. Clin Exp Pharmacol Physiol. 2015 Jun;42(6):720-6. doi: 10.1111/1440-1681.12364. Clin Exp Pharmacol Physiol. 2015. PMID: 25603835 Review.

5

Role of Cys³⁶⁰² in the function and regulation of the cardiac ryanodine receptor.

Mi T, Xiao Z, Guo W, Tang Y, Hiess F, Xiao J, Wang Y, Zhang JZ, Zhang L, Wang R, Jones PP, Chen SR. Mi T, et al. Among authors: jones pp. Biochem J. 2015 Apr 1;467(1):177-90. doi: 10.1042/BJ20141263. Biochem J. 2015. PMID: 25605235

6

Roles of the NH2-terminal domains of cardiac ryanodine receptor in Ca2+ release activation and termination.

Liu Y, Sun B, Xiao Z, Wang R, Guo W, Zhang JZ, Mi T, Wang Y, Jones PP, Van Petegem F, Chen SR. Liu Y, et al. Among authors: jones pp. J Biol Chem. 2015 Mar 20;290(12):7736-46. doi: 10.1074/jbc.M114.618827. Epub 2015 Jan 27. J Biol Chem. 2015. PMID: 25627681 Free PMC article.

7

FKBPs facilitate the termination of spontaneous Ca2+ release in wild-type RyR2 but not CPVT mutant RyR2.

Zhang JZ, Waddell HM, Wu E, Dholakia J, Okolo CA, McLay JC, Jones PP. Zhang JZ, et al. Among authors: jones pp. Biochem J. 2016 Jul 15;473(14):2049-60. doi: 10.1042/BCJ20160389. Epub 2016 May 6. Biochem J. 2016. PMID: 27154203

8

Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias.

Xiao Z, Guo W, Sun B, Hunt DJ, Wei J, Liu Y, Wang Y, Wang R, Jones PP, Back TG, Chen SRW. Xiao Z, et al. Among authors: jones pp. J Biol Chem. 2016 Nov 18;291(47):24528-24537. doi: 10.1074/jbc.M116.756528. Epub 2016 Oct 12. J Biol Chem. 2016. PMID: 27733687 Free PMC article.

9

Control of cardiac ryanodine receptor by sarcoplasmic reticulum luminal Ca².

Jones PP, Guo W, Chen SRW. Jones PP, et al. J Gen Physiol. 2017 Sep 4;149(9):867-875. doi: 10.1085/jgp.201711805. Epub 2017 Aug 10. J Gen Physiol. 2017. PMID: 28798281 Free PMC article. Review.

10

Activation of RyR2 by class I kinase inhibitors.

Chakraborty AD, Gonano LA, Munro ML, Smith LJ, Thekkedam C, Staudacher V, Gamble AB, Macquaide N, Dulhunty AF, Jones PP. Chakraborty AD, et al. Among authors: jones pp. Br J Pharmacol. 2019 Mar;176(6):773-786. doi: 10.1111/bph.14562. Epub 2019 Jan 30. Br J Pharmacol. 2019. PMID: 30588601 Free PMC article.

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