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A New Perspective in the Field of Cardiac Safety Testing through the Comprehensive In Vitro Proarrhythmia Assay Paradigm.
Fermini B, Hancox JC, Abi-Gerges N, Bridgland-Taylor M, Chaudhary KW, Colatsky T, Correll K, Crumb W, Damiano B, Erdemli G, Gintant G, Imredy J, Koerner J, Kramer J, Levesque P, Li Z, Lindqvist A, Obejero-Paz CA, Rampe D, Sawada K, Strauss DG, Vandenberg JI. Fermini B, et al. Among authors: strauss dg. J Biomol Screen. 2016 Jan;21(1):1-11. doi: 10.1177/1087057115594589. Epub 2015 Jul 13. J Biomol Screen. 2016. PMID: 26170255 Review.
Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trial.
Johannesen L, Vicente J, Mason JW, Erato C, Sanabria C, Waite-Labott K, Hong M, Lin J, Guo P, Mutlib A, Wang J, Crumb WJ, Blinova K, Chan D, Stohlman J, Florian J, Ugander M, Stockbridge N, Strauss DG. Johannesen L, et al. Among authors: strauss dg. Clin Pharmacol Ther. 2016 Feb;99(2):214-23. doi: 10.1002/cpt.205. Epub 2015 Nov 28. Clin Pharmacol Ther. 2016. PMID: 26259627 Free PMC article. Clinical Trial.
Sex differences in drug-induced changes in ventricular repolarization.
Vicente J, Johannesen L, Mason JW, Pueyo E, Stockbridge N, Strauss DG. Vicente J, et al. Among authors: strauss dg. J Electrocardiol. 2015 Nov-Dec;48(6):1081-7. doi: 10.1016/j.jelectrocard.2015.08.004. Epub 2015 Aug 4. J Electrocardiol. 2015. PMID: 26324176 Clinical Trial.
Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias.
Blinova K, Stohlman J, Vicente J, Chan D, Johannesen L, Hortigon-Vinagre MP, Zamora V, Smith G, Crumb WJ, Pang L, Lyn-Cook B, Ross J, Brock M, Chvatal S, Millard D, Galeotti L, Stockbridge N, Strauss DG. Blinova K, et al. Among authors: strauss dg. Toxicol Sci. 2017 Jan;155(1):234-247. doi: 10.1093/toxsci/kfw200. Epub 2016 Oct 3. Toxicol Sci. 2017. PMID: 27701120 Free PMC article.
Clinical Trials in a Dish.
Strauss DG, Blinova K. Strauss DG, et al. Trends Pharmacol Sci. 2017 Jan;38(1):4-7. doi: 10.1016/j.tips.2016.10.009. Epub 2016 Nov 19. Trends Pharmacol Sci. 2017. PMID: 27876286 Free PMC article.
187 results