Lo YC - Search Results

1

3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.

Lo YC, Senese S, Damoiseaux R, Torres JZ. Lo YC, et al. ACS Chem Biol. 2016 Aug 19;11(8):2244-53. doi: 10.1021/acschembio.6b00253. Epub 2016 Jun 20. ACS Chem Biol. 2016. PMID: 27285961 Free PMC article.

2

Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens.

Lo YC, Senese S, Li CM, Hu Q, Huang Y, Damoiseaux R, Torres JZ. Lo YC, et al. PLoS Comput Biol. 2015 Mar 31;11(3):e1004153. doi: 10.1371/journal.pcbi.1004153. eCollection 2015 Mar. PLoS Comput Biol. 2015. PMID: 25826798 Free PMC article.

3

Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development.

Senese S, Lo YC, Huang D, Zangle TA, Gholkar AA, Robert L, Homet B, Ribas A, Summers MK, Teitell MA, Damoiseaux R, Torres JZ. Senese S, et al. Among authors: lo yc. Cell Death Dis. 2014 Oct 16;5(10):e1462. doi: 10.1038/cddis.2014.420. Cell Death Dis. 2014. PMID: 25321469 Free PMC article.

4

A unique insertion in STARD9's motor domain regulates its stability.

Senese S, Cheung K, Lo YC, Gholkar AA, Xia X, Wohlschlegel JA, Torres JZ. Senese S, et al. Among authors: lo yc. Mol Biol Cell. 2015 Feb 1;26(3):440-52. doi: 10.1091/mbc.E14-03-0829. Epub 2014 Dec 10. Mol Biol Cell. 2015. PMID: 25501367 Free PMC article.

5

Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential.

Lo YC, Senese S, France B, Gholkar AA, Damoiseaux R, Torres JZ. Lo YC, et al. Sci Rep. 2017 Sep 12;7(1):11261. doi: 10.1038/s41598-017-11508-2. Sci Rep. 2017. PMID: 28900159 Free PMC article.

6

Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation.

Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ. Senese S, et al. Among authors: lo yc. Oncotarget. 2017 Oct 19;8(61):104007-104021. doi: 10.18632/oncotarget.21945. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262617 Free PMC article.

7

Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1.

Xia X, Lo YC, Gholkar AA, Senese S, Ong JY, Velasquez EF, Damoiseaux R, Torres JZ. Xia X, et al. Among authors: lo yc. ACS Chem Biol. 2019 May 17;14(5):994-1001. doi: 10.1021/acschembio.9b00173. Epub 2019 May 8. ACS Chem Biol. 2019. PMID: 31046221 Free PMC article.

8

Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis.

Gholkar AA, Senese S, Lo YC, Capri J, Deardorff WJ, Dharmarajan H, Contreras E, Hodara E, Whitelegge JP, Jackson PK, Torres JZ. Gholkar AA, et al. Among authors: lo yc. Cell Cycle. 2015;14(7):1116-25. doi: 10.4161/15384101.2014.985066. Cell Cycle. 2015. PMID: 25830415 Free PMC article.

9

The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.

Gholkar AA, Senese S, Lo YC, Vides E, Contreras E, Hodara E, Capri J, Whitelegge JP, Torres JZ. Gholkar AA, et al. Among authors: lo yc. Cell Rep. 2016 Jan 12;14(2):180-8. doi: 10.1016/j.celrep.2015.12.035. Epub 2015 Dec 31. Cell Rep. 2016. PMID: 26748699 Free PMC article.

10

Fatostatin Inhibits Cancer Cell Proliferation by Affecting Mitotic Microtubule Spindle Assembly and Cell Division.

Gholkar AA, Cheung K, Williams KJ, Lo YC, Hamideh SA, Nnebe C, Khuu C, Bensinger SJ, Torres JZ. Gholkar AA, et al. Among authors: lo yc. J Biol Chem. 2016 Aug 12;291(33):17001-8. doi: 10.1074/jbc.C116.737346. Epub 2016 Jul 4. J Biol Chem. 2016. PMID: 27378817 Free PMC article.

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