Senese S - Search Results

1

3D Chemical Similarity Networks for Structure-Based Target Prediction and Scaffold Hopping.

Lo YC, Senese S, Damoiseaux R, Torres JZ. Lo YC, et al. Among authors: senese s. ACS Chem Biol. 2016 Aug 19;11(8):2244-53. doi: 10.1021/acschembio.6b00253. Epub 2016 Jun 20. ACS Chem Biol. 2016. PMID: 27285961 Free PMC article.

2

Large-scale chemical similarity networks for target profiling of compounds identified in cell-based chemical screens.

Lo YC, Senese S, Li CM, Hu Q, Huang Y, Damoiseaux R, Torres JZ. Lo YC, et al. Among authors: senese s. PLoS Comput Biol. 2015 Mar 31;11(3):e1004153. doi: 10.1371/journal.pcbi.1004153. eCollection 2015 Mar. PLoS Comput Biol. 2015. PMID: 25826798 Free PMC article.

3

Chemical dissection of the cell cycle: probes for cell biology and anti-cancer drug development.

Senese S, Lo YC, Huang D, Zangle TA, Gholkar AA, Robert L, Homet B, Ribas A, Summers MK, Teitell MA, Damoiseaux R, Torres JZ. Senese S, et al. Cell Death Dis. 2014 Oct 16;5(10):e1462. doi: 10.1038/cddis.2014.420. Cell Death Dis. 2014. PMID: 25321469 Free PMC article.

4

A unique insertion in STARD9's motor domain regulates its stability.

Senese S, Cheung K, Lo YC, Gholkar AA, Xia X, Wohlschlegel JA, Torres JZ. Senese S, et al. Mol Biol Cell. 2015 Feb 1;26(3):440-52. doi: 10.1091/mbc.E14-03-0829. Epub 2014 Dec 10. Mol Biol Cell. 2015. PMID: 25501367 Free PMC article.

5

Structures of potent anticancer compounds bound to tubulin.

McNamara DE, Senese S, Yeates TO, Torres JZ. McNamara DE, et al. Among authors: senese s. Protein Sci. 2015 Jul;24(7):1164-72. doi: 10.1002/pro.2704. Epub 2015 May 27. Protein Sci. 2015. PMID: 25970265 Free PMC article.

6

NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.

Chan AH, Yi SW, Weiner EM, Amer BR, Sue CK, Wereszczynski J, Dillen CA, Senese S, Torres JZ, McCammon JA, Miller LS, Jung ME, Clubb RT. Chan AH, et al. Among authors: senese s. Chem Biol Drug Des. 2017 Sep;90(3):327-344. doi: 10.1111/cbdd.12962. Epub 2017 Mar 6. Chem Biol Drug Des. 2017. PMID: 28160417 Free PMC article.

7

Computational Cell Cycle Profiling of Cancer Cells for Prioritizing FDA-Approved Drugs with Repurposing Potential.

Lo YC, Senese S, France B, Gholkar AA, Damoiseaux R, Torres JZ. Lo YC, et al. Among authors: senese s. Sci Rep. 2017 Sep 12;7(1):11261. doi: 10.1038/s41598-017-11508-2. Sci Rep. 2017. PMID: 28900159 Free PMC article.

8

Microtubins: a novel class of small synthetic microtubule targeting drugs that inhibit cancer cell proliferation.

Senese S, Lo YC, Gholkar AA, Li CM, Huang Y, Mottahedeh J, Kornblum HI, Damoiseaux R, Torres JZ. Senese S, et al. Oncotarget. 2017 Oct 19;8(61):104007-104021. doi: 10.18632/oncotarget.21945. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262617 Free PMC article.

9

Leukemia Cell Cycle Chemical Profiling Identifies the G2-Phase Leukemia Specific Inhibitor Leusin-1.

Xia X, Lo YC, Gholkar AA, Senese S, Ong JY, Velasquez EF, Damoiseaux R, Torres JZ. Xia X, et al. Among authors: senese s. ACS Chem Biol. 2019 May 17;14(5):994-1001. doi: 10.1021/acschembio.9b00173. Epub 2019 May 8. ACS Chem Biol. 2019. PMID: 31046221 Free PMC article.

10

Dynamic and multi-pharmacophore modeling for designing polo-box domain inhibitors.

Sakkiah S, Senese S, Yang Q, Lee KW, Torres JZ. Sakkiah S, et al. Among authors: senese s. PLoS One. 2014 Jul 18;9(7):e101405. doi: 10.1371/journal.pone.0101405. eCollection 2014. PLoS One. 2014. PMID: 25036740 Free PMC article.

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