Beauchamp EM - Search Results

1

Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.

Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC. Kosciuczuk EM, et al. Among authors: beauchamp em. Blood. 2016 Jul 21;128(3):410-4. doi: 10.1182/blood-2016-02-698704. Epub 2016 Jun 15. Blood. 2016. PMID: 27307295 Free PMC article.

2

BH3 mimetics and multi-kinase inhibition in AML.

Beauchamp EM, Platanias LC. Beauchamp EM, et al. Blood. 2012 Jun 21;119(25):5947-8. doi: 10.1182/blood-2012-04-420786. Blood. 2012. PMID: 22730522 Free article.

3

The evolution of the TOR pathway and its role in cancer.

Beauchamp EM, Platanias LC. Beauchamp EM, et al. Oncogene. 2013 Aug 22;32(34):3923-32. doi: 10.1038/onc.2012.567. Epub 2012 Dec 17. Oncogene. 2013. PMID: 23246968 Review.

4

Resveratrol enhances the suppressive effects of arsenic trioxide on primitive leukemic progenitors.

Wu EJ, Goussetis DJ, Beauchamp E, Kosciuczuk EM, Altman JK, Eklund EA, Platanias LC. Wu EJ, et al. Among authors: beauchamp e. Cancer Biol Ther. 2014 Apr;15(4):473-8. doi: 10.4161/cbt.27824. Epub 2014 Feb 4. Cancer Biol Ther. 2014. PMID: 24496081 Free PMC article.

5

Autophagy is a survival mechanism of acute myelogenous leukemia precursors during dual mTORC2/mTORC1 targeting.

Altman JK, Szilard A, Goussetis DJ, Sassano A, Colamonici M, Gounaris E, Frankfurt O, Giles FJ, Eklund EA, Beauchamp EM, Platanias LC. Altman JK, et al. Among authors: beauchamp em. Clin Cancer Res. 2014 May 1;20(9):2400-9. doi: 10.1158/1078-0432.CCR-13-3218. Epub 2014 Mar 7. Clin Cancer Res. 2014. PMID: 24610825 Free PMC article.

6

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.

Eckerdt F, Beauchamp E, Bell J, Iqbal A, Su B, Fukunaga R, Lulla RR, Goldman S, Platanias LC. Eckerdt F, et al. Oncotarget. 2014 Sep 30;5(18):8442-51. doi: 10.18632/oncotarget.2319. Oncotarget. 2014. PMID: 25193863 Free PMC article.

7

Overcoming treatment challenges in imatinib-resistant chronic myelogenous leukemia.

Curi DA, Beauchamp EM, Platanias LC. Curi DA, et al. Among authors: beauchamp em. Leuk Lymphoma. 2015 Jun;56(6):1581-2. doi: 10.3109/10428194.2014.970549. Epub 2014 Nov 5. Leuk Lymphoma. 2015. PMID: 25284498 No abstract available.

8

Direct binding of arsenic trioxide to AMPK and generation of inhibitory effects on acute myeloid leukemia precursors.

Beauchamp EM, Kosciuczuk EM, Serrano R, Nanavati D, Swindell EP, Viollet B, O'Halloran TV, Altman JK, Platanias LC. Beauchamp EM, et al. Mol Cancer Ther. 2015 Jan;14(1):202-12. doi: 10.1158/1535-7163.MCT-14-0665-T. Epub 2014 Oct 24. Mol Cancer Ther. 2015. PMID: 25344585 Free PMC article.

9

Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase.

Colamonici M, Blyth G, Saleiro D, Szilard A, Bliss-Moreau M, Giles FJ, Altman JK, Beauchamp EM, Platanias LC. Colamonici M, et al. Among authors: beauchamp em. Oncotarget. 2015 Apr 10;6(10):8062-70. doi: 10.18632/oncotarget.3509. Oncotarget. 2015. PMID: 25823922 Free PMC article.

10

Central role of ULK1 in type I interferon signaling.

Saleiro D, Mehrotra S, Kroczynska B, Beauchamp EM, Lisowski P, Majchrzak-Kita B, Bhagat TD, Stein BL, McMahon B, Altman JK, Kosciuczuk EM, Baker DP, Jie C, Jafari N, Thompson CB, Levine RL, Fish EN, Verma AK, Platanias LC. Saleiro D, et al. Among authors: beauchamp em. Cell Rep. 2015 Apr 28;11(4):605-17. doi: 10.1016/j.celrep.2015.03.056. Epub 2015 Apr 16. Cell Rep. 2015. PMID: 25892232 Free PMC article.

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