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Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo.
Storti P, Marchica V, Airoldi I, Donofrio G, Fiorini E, Ferri V, Guasco D, Todoerti K, Silbermann R, Anderson JL, Zhao W, Agnelli L, Bolzoni M, Martella E, Mancini C, Campanini N, Noonan DM, Petronini PG, Neri A, Aversa F, Roodman GD, Giuliani N. Storti P, et al. Among authors: roodman gd. Leukemia. 2016 Dec;30(12):2351-2363. doi: 10.1038/leu.2016.137. Epub 2016 May 20. Leukemia. 2016. PMID: 27311934
Hypoxia-inducible factor (HIF)-1α suppression in myeloma cells blocks tumoral growth in vivo inhibiting angiogenesis and bone destruction.
Storti P, Bolzoni M, Donofrio G, Airoldi I, Guasco D, Toscani D, Martella E, Lazzaretti M, Mancini C, Agnelli L, Patrene K, Maïga S, Franceschi V, Colla S, Anderson J, Neri A, Amiot M, Aversa F, Roodman GD, Giuliani N. Storti P, et al. Among authors: roodman gd. Leukemia. 2013 Aug;27(8):1697-706. doi: 10.1038/leu.2013.24. Epub 2013 Jan 24. Leukemia. 2013. PMID: 23344526
Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo.
Teramachi J, Silbermann R, Yang P, Zhao W, Mohammad KS, Guo J, Anderson JL, Zhou D, Feng R, Myint KZ, Maertz N, Beumer JH, Eiseman JL, Windle JJ, Xie XQ, Roodman GD, Kurihara N. Teramachi J, et al. Among authors: roodman gd. Leukemia. 2016 Feb;30(2):390-8. doi: 10.1038/leu.2015.229. Epub 2015 Aug 19. Leukemia. 2016. PMID: 26286116 Free PMC article.
Myeloma bone disease: Pathophysiology and management.
Silbermann R, Roodman GD. Silbermann R, et al. Among authors: roodman gd. J Bone Oncol. 2013 Apr 18;2(2):59-69. doi: 10.1016/j.jbo.2013.04.001. eCollection 2013 Jun. J Bone Oncol. 2013. PMID: 26909272 Free PMC article. Review.
Mechanisms of multiple myeloma bone disease.
Galson DL, Silbermann R, Roodman GD. Galson DL, et al. Among authors: roodman gd. Bonekey Rep. 2012 Aug 1;1:135. doi: 10.1038/bonekey.2012.135. eCollection 2012. Bonekey Rep. 2012. PMID: 23951515 Free PMC article.
297 results