Guguen-Guillouzo C - Search Results

1

Differential sensitivity of metabolically competent and non-competent HepaRG cells to apoptosis induced by diclofenac combined or not with TNF-α.

Al-Attrache H, Sharanek A, Burban A, Burbank M, Gicquel T, Abdel-Razzak Z, Guguen-Guillouzo C, Morel I, Guillouzo A. Al-Attrache H, et al. Toxicol Lett. 2016 Sep 6;258:71-86. doi: 10.1016/j.toxlet.2016.06.008. Epub 2016 Jun 14. Toxicol Lett. 2016. PMID: 27313093 Free article.

2

Stem cell-derived hepatocytes and their use in toxicology.

Guguen-Guillouzo C, Corlu A, Guillouzo A. Guguen-Guillouzo C, et al. Toxicology. 2010 Mar 30;270(1):3-9. doi: 10.1016/j.tox.2009.09.019. Epub 2009 Oct 6. Toxicology. 2010. PMID: 19815049 Review.

3

Different dose-dependent mechanisms are involved in early cyclosporine a-induced cholestatic effects in hepaRG cells.

Sharanek A, Azzi PB, Al-Attrache H, Savary CC, Humbert L, Rainteau D, Guguen-Guillouzo C, Guillouzo A. Sharanek A, et al. Toxicol Sci. 2014 Sep;141(1):244-53. doi: 10.1093/toxsci/kfu122. Epub 2014 Jun 27. Toxicol Sci. 2014. PMID: 24973091 Free PMC article.

4

Impact of inflammation on chlorpromazine-induced cytotoxicity and cholestatic features in HepaRG cells.

Bachour-El Azzi P, Sharanek A, Abdel-Razzak Z, Antherieu S, Al-Attrache H, Savary CC, Lepage S, Morel I, Labbe G, Guguen-Guillouzo C, Guillouzo A. Bachour-El Azzi P, et al. Drug Metab Dispos. 2014 Sep;42(9):1556-66. doi: 10.1124/dmd.114.058123. Epub 2014 Jul 7. Drug Metab Dispos. 2014. PMID: 25002748

5

Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes.

Bachour-El Azzi P, Sharanek A, Burban A, Li R, Guével RL, Abdel-Razzak Z, Stieger B, Guguen-Guillouzo C, Guillouzo A. Bachour-El Azzi P, et al. Toxicol Sci. 2015 May;145(1):157-68. doi: 10.1093/toxsci/kfv041. Epub 2015 Feb 17. Toxicol Sci. 2015. PMID: 25690737 Free PMC article.

6

Setup and Use of HepaRG Cells in Cholestasis Research.

Guguen-Guillouzo C, Guillouzo A. Guguen-Guillouzo C, et al. Methods Mol Biol. 2019;1981:291-312. doi: 10.1007/978-1-4939-9420-5_19. Methods Mol Biol. 2019. PMID: 31016662

7

Evolving concepts in liver tissue modeling and implications for in vitro toxicology.

Guillouzo A, Guguen-Guillouzo C. Guillouzo A, et al. Expert Opin Drug Metab Toxicol. 2008 Oct;4(10):1279-94. doi: 10.1517/17425255.4.10.1279. Expert Opin Drug Metab Toxicol. 2008. PMID: 18798698 Review.

8

Differential toxicity of heterocyclic aromatic amines and their mixture in metabolically competent HepaRG cells.

Dumont J, Jossé R, Lambert C, Anthérieu S, Le Hegarat L, Aninat C, Robin MA, Guguen-Guillouzo C, Guillouzo A. Dumont J, et al. Toxicol Appl Pharmacol. 2010 Jun 1;245(2):256-63. doi: 10.1016/j.taap.2010.03.008. Epub 2010 Mar 20. Toxicol Appl Pharmacol. 2010. PMID: 20307560

9

Optimization of the HepaRG cell model for drug metabolism and toxicity studies.

Anthérieu S, Chesné C, Li R, Guguen-Guillouzo C, Guillouzo A. Anthérieu S, et al. Toxicol In Vitro. 2012 Dec;26(8):1278-85. doi: 10.1016/j.tiv.2012.05.008. Epub 2012 May 27. Toxicol In Vitro. 2012. PMID: 22643240 Review.

10

Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells.

Anthérieu S, Bachour-El Azzi P, Dumont J, Abdel-Razzak Z, Guguen-Guillouzo C, Fromenty B, Robin MA, Guillouzo A. Anthérieu S, et al. Hepatology. 2013 Apr;57(4):1518-29. doi: 10.1002/hep.26160. Epub 2013 Mar 4. Hepatology. 2013. PMID: 23175273

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