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Serine racemase binds to PICK1: potential relevance to schizophrenia.
Fujii K, Maeda K, Hikida T, Mustafa AK, Balkissoon R, Xia J, Yamada T, Ozeki Y, Kawahara R, Okawa M, Huganir RL, Ujike H, Snyder SH, Sawa A. Fujii K, et al. Among authors: hikida t. Mol Psychiatry. 2006 Feb;11(2):150-7. doi: 10.1038/sj.mp.4001776. Mol Psychiatry. 2006. PMID: 16314870 Clinical Trial.
Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans.
Hikida T, Jaaro-Peled H, Seshadri S, Oishi K, Hookway C, Kong S, Wu D, Xue R, Andradé M, Tankou S, Mori S, Gallagher M, Ishizuka K, Pletnikov M, Kida S, Sawa A. Hikida T, et al. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14501-6. doi: 10.1073/pnas.0704774104. Epub 2007 Aug 3. Proc Natl Acad Sci U S A. 2007. PMID: 17675407 Free PMC article.
Modulation of D-serine levels in brains of mice lacking PICK1.
Hikida T, Mustafa AK, Maeda K, Fujii K, Barrow RK, Saleh M, Huganir RL, Snyder SH, Hashimoto K, Sawa A. Hikida T, et al. Biol Psychiatry. 2008 May 15;63(10):997-1000. doi: 10.1016/j.biopsych.2007.09.025. Epub 2008 Jan 11. Biol Psychiatry. 2008. PMID: 18191108 Free PMC article.
DISC1 as a therapeutic target for mental illnesses.
Hikida T, Gamo NJ, Sawa A. Hikida T, et al. Expert Opin Ther Targets. 2012 Dec;16(12):1151-60. doi: 10.1517/14728222.2012.719879. Epub 2012 Nov 6. Expert Opin Ther Targets. 2012. PMID: 23130881 Free PMC article. Review.
131 results