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823 results

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Page 1
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
Giles K, Berry DB, Condello C, Dugger BN, Li Z, Oehler A, Bhardwaj S, Elepano M, Guan S, Silber BM, Olson SH, Prusiner SB. Giles K, et al. Among authors: bhardwaj s. J Pharmacol Exp Ther. 2016 Sep;358(3):537-47. doi: 10.1124/jpet.116.235556. Epub 2016 Jun 17. J Pharmacol Exp Ther. 2016. PMID: 27317802 Free PMC article.
Drug resistance confounding prion therapeutics.
Berry DB, Lu D, Geva M, Watts JC, Bhardwaj S, Oehler A, Renslo AR, DeArmond SJ, Prusiner SB, Giles K. Berry DB, et al. Among authors: bhardwaj s. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4160-9. doi: 10.1073/pnas.1317164110. Epub 2013 Oct 15. Proc Natl Acad Sci U S A. 2013. PMID: 24128760 Free PMC article.
Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.
Watts JC, Giles K, Serban A, Patel S, Oehler A, Bhardwaj S, Guan S, Greicius MD, Miller BL, DeArmond SJ, Geschwind MD, Prusiner SB. Watts JC, et al. Among authors: bhardwaj s. Ann Neurol. 2015 Oct;78(4):540-53. doi: 10.1002/ana.24463. Epub 2015 Aug 25. Ann Neurol. 2015. PMID: 26094969 Free PMC article.
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
Giles K, Berry DB, Condello C, Hawley RC, Gallardo-Godoy A, Bryant C, Oehler A, Elepano M, Bhardwaj S, Patel S, Silber BM, Guan S, DeArmond SJ, Renslo AR, Prusiner SB. Giles K, et al. Among authors: bhardwaj s. J Pharmacol Exp Ther. 2015 Oct;355(1):2-12. doi: 10.1124/jpet.115.224659. Epub 2015 Jul 29. J Pharmacol Exp Ther. 2015. PMID: 26224882 Free PMC article.
Towards authentic transgenic mouse models of heritable PrP prion diseases.
Watts JC, Giles K, Bourkas ME, Patel S, Oehler A, Gavidia M, Bhardwaj S, Lee J, Prusiner SB. Watts JC, et al. Among authors: bhardwaj s. Acta Neuropathol. 2016 Oct;132(4):593-610. doi: 10.1007/s00401-016-1585-6. Epub 2016 Jun 28. Acta Neuropathol. 2016. PMID: 27350609 Free PMC article.
Protease-resistant prions selectively decrease Shadoo protein.
Watts JC, Stöhr J, Bhardwaj S, Wille H, Oehler A, Dearmond SJ, Giles K, Prusiner SB. Watts JC, et al. Among authors: bhardwaj s. PLoS Pathog. 2011 Nov;7(11):e1002382. doi: 10.1371/journal.ppat.1002382. Epub 2011 Nov 17. PLoS Pathog. 2011. PMID: 22163178 Free PMC article.
823 results